CRYGD and CRYGC

Number of citations of the paper that reports this interaction (PMID 12601044)
21

Data Source:
BioGRID (two hybrid)

		CRYGD	CRYGC
Gene Name		crystallin, gamma D	crystallin, gamma C
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception Cellular Response To Reactive Oxygen Species Lens Fiber Cell Differentiation	Visual Perception Camera-type Eye Development
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		3 interactors: CRYAA CRYAB CRYGC	7 interactors: CRYAA CRYAB CRYBB2 CRYGD HSPB1 HSPB2 MIP
Entrez ID		1421	1420
HPRD ID		00436	00435
Ensembl ID		ENSG00000118231	ENSG00000163254
Uniprot IDs		P07320	P07315
PDB IDs		1H4A 1HK0 1LD0 2G98 2KFB 2KLJ 4GR7 4JGF	1LFE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Intracellular Transport Visual Perception Sensory Perception Of Light Stimulus Protein Homooligomerization Camera-type Eye Development Negative Regulation Of Transport Eye Development Tubulin Complex Assembly Protein Oligomerization Regulation Of Intracellular Transport Sensory Organ Development Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Apoptotic Process Involved In Development Sensory Perception Negative Regulation Of Apoptotic Process Developmental Programmed Cell Death Negative Regulation Of Programmed Cell Death Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Death Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Complex Assembly Regulation Of Cellular Localization Response To Gamma Radiation Neurological System Process Cellular Response To Ionizing Radiation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Lens Development In Camera-type Eye Regulation Of Cell Death Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Response To Estradiol Response To Hydrogen Peroxide	Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Lens Development In Camera-type Eye Eye Development Sensory Organ Development Sensory Perception Neurological System Process Negative Regulation Of Intracellular Transport Response To Stimulus Response To Unfolded Protein Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Reactive Oxygen Species Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Cell Death Tubulin Complex Assembly Protein Homooligomerization Positive Regulation Of Endothelial Cell Chemotaxis Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Response To Oxidative Stress Organ Development Protein Oligomerization Regulation Of Apoptotic Process Regulation Of Intracellular Transport Apoptotic Process Involved In Development Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Bile Acid And Bile Salt Transport Cell Volume Homeostasis
Tagcloud ?		2j 6v2 beadchip bxd crosses cryab cryba1 crybb3 cryga crystallin crystallins dba extralenticular genenetwork genomatix hamilton hei hle hlec illumina immunoblots inbred maf mafa mousewg retina rgc ri sentrix	coherence cryba1 cryba2 cryba4 crybb1 crybb2 crybb3 crystallin degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retina retinal retinopathies rpe survived
Tagcloud (Difference) ?		2j 6v2 beadchip bxd crosses cryab cryga crystallins dba extralenticular genenetwork genomatix hamilton hei hle hlec illumina immunoblots inbred maf mafa mousewg rgc ri sentrix	coherence cryba2 cryba4 crybb1 crybb2 degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retinal retinopathies rpe survived
Tagcloud (Intersection) ?		cryba1 crybb3 crystallin retina