CRIP1 and SH3GL3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRIP1	SH3GL3
Gene Name		cysteine-rich protein 1 (intestinal)	SH3-domain GRB2-like 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Early Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	AT DNA Binding Zinc Ion Binding DNA Binding, Bending Peptide Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Immune Response Heart Development Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Organic Substance Response To Zinc Ion Regulation Of Gene Expression Prostate Gland Stromal Morphogenesis Cellular Response To Antibiotic Cellular Response To UV-B	Endocytosis Signal Transduction Central Nervous System Development
Pathways
Drugs
Diseases
GWAS			Height ( 18391950 18391951 20397748)
Protein-Protein Interactions		3 interactors: GPRASP1 HAP1 SH3GL3	44 interactors: ADRB1 AES ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNM1 DPPA4 DPYSL4 EGFL6 EMD FAM173A FASLG GABBR2 HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RBM48 RER1 RPL35A SEPT8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHC3 SNRPN SNX24 SYNJ1 TERF1 TNNT1 TOE1 VIM WASL WDR33
Entrez ID		1396	6457
HPRD ID		00469	04528
Ensembl ID		ENSG00000213145	ENSG00000140600
Uniprot IDs		P50238	Q99963
PDB IDs			2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly G-protein Coupled Receptor Catabolic Process Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Retrograde Axon Cargo Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Positive Regulation Of Synaptic Transmission, GABAergic Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration DNA Demethylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Receptor Catabolic Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Beta-amyloid Formation Regulation Of Cilium Assembly Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Anterograde Axon Cargo Transport Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Endosome To Lysosome Transport Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cation Channel Activity DNA Catabolic Process, Exonucleolytic Vesicle Transport Along Microtubule Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of DNA Repair Central Nervous System Development Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Receptor Activity Regulation Of Smooth Muscle Cell Migration Lysosomal Transport Cellular Response To CAMP Positive Regulation Of Ion Transmembrane Transporter Activity Axon Cargo Transport Regulation Of MRNA Stability	Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signaling Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Signal Transduction Vesicle-mediated Transport Cell Communication Movement Of Cell Or Subcellular Component Regulation Of Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Cell Death Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Membrane Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Negative Regulation Of ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Developmental Process System Development Neuron Development Apoptotic Process Cellular Process Generation Of Neurons Actin Filament-based Movement Multicellular Organismal Development Nervous System Development Programmed Cell Death Regulation Of Signaling Neurogenesis Regulation Of Endocytosis Regulation Of Signal Transduction Negative Regulation Of Neuron Differentiation Neuron Projection Development Establishment Of Vesicle Localization Synaptic Transmission Positive Regulation Of Apoptotic Process Cell Projection Morphogenesis Neuron Differentiation Vesicle Localization Response To Growth Factor Axon Guidance Neurotrophin TRK Receptor Signaling Pathway Cell Part Morphogenesis
Tagcloud ?		activate bt474 cdc2 characterization cysteine distant downregulated ductal elucidate endogenous hypothesize immunoblotting intestinal invasion kaplan knockdown meier metastases nodal power prognosis prognostic prognosticators revealing rich t47d transiently worse wst	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Difference) ?		activate bt474 cdc2 characterization cysteine distant downregulated ductal elucidate endogenous hypothesize immunoblotting intestinal invasion kaplan knockdown meier metastases nodal power prognosis prognostic prognosticators revealing rich t47d transiently worse wst	85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Intersection) ?