CRIP1 and SH3GL3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRIP1	SH3GL3
Description		cysteine rich protein 1	SH3 domain containing GRB2 like 3, endophilin A3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Acrosomal Vesicle Cytoplasm Endosome Early Endosome Membrane Early Endosome Membrane Presynapse Postsynaptic Endosome Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Zinc Ion Binding Peptide Binding Metal Ion Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Immune Response Heart Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Zinc Ion Regulation Of Gene Expression Prostate Gland Stromal Morphogenesis Cellular Response To Antibiotic Cellular Response To UV-B	Endocytosis Signal Transduction Central Nervous System Development Positive Regulation Of Neuron Differentiation Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis
Pathways			EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell NGF-stimulated transcription
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)	A body shape index ( 34021172) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate after 5 years in renal transplantation (recipient effect) ( 30920136) FEV1 ( 30804560) Gynecologic disease (multivariate analysis) ( 31488892) Height ( 18391951 28552196 25282103 20397748 18391950) Hip circumference adjusted for BMI ( 28552196 34021172) Hip index ( 34021172) Lung function (FEV1/FVC) ( 28166213 30804560) Proteinuria and chronic kidney disease ( 26420894) Smoking initiation ( 33082346) Spine bone size ( 31053729) Waist circumference adjusted for body mass index ( 34021172) Working memory ( 31598132)
Interacting Genes		4 interacting genes: GPRASP1 HAP1 SH3GL3 STUB1	52 interacting genes: ADRB1 ANTKMT ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNAJC5 DNM1 DPPA4 DPYSL4 EGFL6 EGFR EMD FASLG FBXO32 GABBR2 GOLT1B HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RABAC1 RBM48 RER1 RNF8 RPL35A SEPTIN8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHANK3 SHC3 SNRPN SNX24 SYNJ1 TERF1 TLE5 TMEM120B TNNT1 TOE1 VIM WASL WDR33
Entrez ID		1396	6457
HPRD ID		00469	04528
Ensembl ID		ENSG00000213145	ENSG00000140600
Uniprot IDs		P50238	Q99963
PDB IDs			2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Presynapse Positive Regulation Of Cellular Component Organization Regulation Of Cellular Component Organization Regulation Of Receptor-mediated Endocytosis Regulation Of Cellular Localization Endocytosis Intracellular Transport Regulation Of Vesicle-mediated Transport Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Response To Butyrate ERBB Signaling Pathway Cellular Response To Hydrostatic Pressure Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Neurotrophin Production Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity G Protein-coupled Receptor Catabolic Process Negative Regulation Of Vascular Associated Smooth Muscle Contraction Positive Regulation Of Chaperone-mediated Protein Complex Assembly I-kappaB Phosphorylation Synaptic Vesicle Transmembrane Transporter Binding Import Into Cell Signal Sequence Binding Phosphatidylinositol 3-kinase Complex, Class IB Negative Regulation Of Clathrin-dependent Endocytosis Ubiquitin Conjugating Enzyme Complex Cellular Localization Enzyme-linked Receptor Protein Signaling Pathway Establishment Of Localization In Cell Regulation Of Protein Localization To Membrane Extrinsic Component Of Presynaptic Endocytic Zone Membrane Postsynaptic Endosome Hypothalamus Cell Differentiation Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Synaptic Vesicle Recycling Postsynaptic Neurotransmitter Receptor Internalization Autosome Genomic Imprinting Response To Muscle Inactivity Phosphatidylinositol 3-kinase Complex 1-phosphatidylinositol-4-phosphate 3-kinase Activity Negative Regulation Of Fibroblast Apoptotic Process Regulation Of Macroautophagy 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Response To Hydrostatic Pressure Chaperone-mediated Autophagy TPR Domain Binding	Presynapse Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of CAMKK-AMPK Signaling Cascade Presynaptic Cytosol Central Nervous System Development Cytoplasmic Side Of Mitochondrial Outer Membrane Cytoplasm Negative Regulation Of ERBB Signaling Pathway Cytoplasmic Vesicle Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Vocal Learning Observational Learning Synapse
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