ZNF513 and PPARGC1B

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZNF513	PPARGC1B
Gene Name		zinc finger protein 513	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mitochondrion Mediator Complex
	Molecular Function	DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Receptor Activator Activity AF-2 Domain Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Visual Perception Response To Stimulus Retina Development In Camera-type Eye	Ossification Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Receptor Activity
Pathways			PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Tanning ( 19340012)
Protein-Protein Interactions		4 interactors: KAT5 PPARGC1B ZFP64 ZZZ3	13 interactors: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513
Entrez ID		130557	133522
HPRD ID		15813	10594
Ensembl ID		ENSG00000163795	ENSG00000155846
Uniprot IDs		Q8N8E2	B7ZM40 Q86YN6
PDB IDs			3SP6
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Intracellular Receptor Signaling Pathway Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Transcription From Mitochondrial Promoter Regulation Of Gene Expression Bone Trabecula Formation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Response To Steroid Hormone Positive Regulation Of Alkaline Phosphatase Activity Positive Regulation Of Bone Resorption Nitrogen Compound Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Bone Trabecula Morphogenesis Cellular Response To Estradiol Stimulus Negative Regulation Of Interleukin-2 Production Positive Regulation Of Protein Acetylation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Estrogen Stimulus Positive Regulation Of Tissue Remodeling Chromatin Organization Positive Regulation Of Phosphatase Activity Regulation Of Bone Resorption Positive Regulation Of RNA Splicing Androgen Receptor Signaling Pathway Positive Regulation Of Receptor Activity Response To Lipid Regulation Of Bone Remodeling Response To Organic Cyclic Compound Positive Regulation Of Dephosphorylation Trabecula Morphogenesis Organelle Organization	Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Receptor Signaling Pathway Transcription, DNA-templated Cellular Response To Organic Cyclic Compound RNA Biosynthetic Process Gene Expression Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Hormone-mediated Signaling Pathway Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Lipid Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Response To Steroid Hormone DNA-templated Transcription, Initiation Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Lipid Metabolic Process Cellular Metabolic Process Mammary Gland Epithelium Development Cellular Response To Organic Substance Regulation Of Glucose Metabolic Process Uterus Development Regulation Of Fatty Acid Beta-oxidation Intracellular Estrogen Receptor Signaling Pathway
Tagcloud ?			17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Difference) ?			17beta abundantly biased coagulation constituted dimorphic dimorphism etc feminized hnf4a insensitive keto kt11 livers lxr metabolisms mycn oviparous retinol sage sexes spawning stat4 transcriptomes transcriptomic vitellogenin viviparous xenobiotic zebrafish
Tagcloud (Intersection) ?