CNR2 and MUC15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNR2	MUC15
Description		cannabinoid receptor 2	mucin 15, cell surface associated
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cell Projection Neuronal Cell Body Perikaryon Postsynaptic Membrane	Extracellular Region Golgi Lumen Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding	Protein Binding
	Biological Process	Response To Amphetamine Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Leukocyte Chemotaxis Negative Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Cannabinoid Signaling Pathway Negative Regulation Of Action Potential Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events	Defective GALNT3 causes HFTC Defective C1GALT1C1 causes TNPS Defective GALNT12 causes CRCS1 Dectin-2 family O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs		Dronabinol Nabilone Ricinoleic acid Lasofoxifene Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols S-777469
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Psychotic experience (distressing) ( 31553412)	Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Exhaled nitric oxide levels ( 28109725) Exhaled nitric oxide output ( 28109725) Obesity (extreme) ( 19553259)
Interacting Genes		24 interacting genes: ADAM21 ADIPOQ AGPAT4 CCL4 COMT FXYD3 GNA15 MUC15 NRM PEDS1-UBE2V1 RFT1 SELENOK SLC35E4 SLC39A2 TMEM19 TMEM203 TMEM242 TMEM60 TMEM86A TMPPE TSPO2 YIPF1 YIPF4 YIPF6	2 interacting genes: CD3E CNR2
Entrez ID		1269	143662
HPRD ID		05444	16349
Ensembl ID		ENSG00000188822	ENSG00000169550
Uniprot IDs		P34972	A0A0A0MT67 A0A0A0MTD6 Q8N387
PDB IDs		2KI9 5ZTY 6KPC 6KPF 6PT0 8GUQ 8GUR 8GUS 8GUT 8X3L
Enriched GO Terms of Interacting Partners?		Membrane Golgi Trans Cisterna Golgi Medial Cisterna Endoplasmic Reticulum Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Positive Regulation Of T Cell Anergy Alpha-beta T Cell Receptor Complex Signal Complex Assembly Positive Regulation Of Tolerance Induction Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Thymic T Cell Selection T Cell Receptor Binding T Cell Tolerance Induction Regulation Of Cell-cell Adhesion Mediated By Integrin Regulation Of T Cell Anergy Negative Thymic T Cell Selection Negative T Cell Selection CD4-positive, Alpha-beta T Cell Proliferation T Cell Anergy Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Tolerance Induction Regulation Of Cell Activation Gamma-delta T Cell Receptor Complex Regulation Of T Cell Tolerance Induction Cannabinoid Receptor Activity Negative Regulation Of Action Potential Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission Trans-synaptic Signaling, Modulating Synaptic Transmission Cannabinoid Signaling Pathway Negative Regulation Of Synaptic Transmission, GABAergic Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Negative Regulation Of Mast Cell Activation Positive T Cell Selection Alpha-beta T Cell Proliferation G Protein-coupled Receptor Signaling Pathway Regulation Of Tolerance Induction Tolerance Induction T Cell Receptor Complex Regulation Of Mast Cell Activation Gamma-delta T Cell Activation Thymic T Cell Selection Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Interleukin-4 Production T Cell Selection Response To Amphetamine Signaling Receptor Complex Adaptor Activity Regulation Of Interleukin-4 Production Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Interleukin-2 Production Negative Regulation Of Synaptic Transmission Immune Response Dendrite Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?