CNR2

Gene Name		cannabinoid receptor 2 (macrophage)
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perikaryon
	Molecular Function	Cannabinoid Receptor Activity
	Biological Process	Response To Amphetamine Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Sensory Perception Of Pain Negative Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Cannabinoid Signaling Pathway Negative Regulation Of Action Potential Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Dronabinol Nabilone
Diseases
GWAS
Protein-protein Interactions		1 interactors: GNA15
Entrez ID		1269
HPRD ID		05444
Ensembl ID		ENSG00000188822
Uniprot IDs		C6ES44 P34972
PDB IDs		2KI9
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway G-protein Coupled Acetylcholine Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Platelet Activation Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Blood Coagulation Hemostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Cellular Homeostasis Response To Wounding
Tagcloud ?		abstract acts autoimmune cannabinoid case cb2 cb2r diseases drugs due era heterogeneous immune itp k2 literature marijuana mimetics pathogenesis polymorphisms prednisolone presented receptors secondary successfully synthetic thrombocytes thrombocytopenia usage