SLAIN1 and TBC1D22B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLAIN1	TBC1D22B
Description		SLAIN motif family member 1	TBC1 domain family member 22B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Plus-end	Golgi Apparatus
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding 14-3-3 Protein Binding
	Biological Process	Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization	Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Craniofacial microsomia ( 26853712) Metabolite levels ( 23823483)	Acne (severe) ( 24927181) Blood glucose levels ( 31928498) Platelet count ( 27863252) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498)
Interacting Genes		50 interacting genes: AIRIM AKAP9 ARHGEF5 ARMC7 ATOSB BCAS2 CARD9 COX5B CPSF7 CRACR2A DDX6 DMRTB1 EFHC1 EXOSC8 FBXO7 FHL2 FHL3 FRS3 GOLGA1 HNRNPF HOMER3 HOXC8 HSF2BP KCTD9 KIF9 KRT31 LMO3 MAPRE1 MAPRE3 NDEL1 NTAQ1 NXF1 PATZ1 PAX9 PDLIM7 PFDN5 PRC1 PRPF31 PSMA3 QKI RBM10 RBM14 RBPMS RFPL3 SAXO4 SIAH1 TBC1D22B TFAP2D TSSK3 ZNF76	58 interacting genes: AP1B1 ARHGEF9 BLZF1 CALCOCO2 CARD10 CCDC57 CCDC88B CDR2 CEP63 CEP70 COG6 DAPK1 DDIT4L DEUP1 EFHC2 EXOC8 FHL3 FXR1 FXR2 GFAP GOLGA2 HMG20A HOMER3 HOOK2 HSD17B14 IKZF3 KIFC3 KRT34 KRT40 LHX8 LIMS1 LRRK2 MFHAS1 MID2 MTUS2 PICK1 PLEKHG4 PNMA5 RBM10 RBM48 REL SIAH1 SLAIN1 SORBS3 SPATA2 TACC3 TEPSIN TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 TRIP6 VPS52 ZFP90 ZNF438 ZNF76 ZSCAN4
Entrez ID		122060	55633
HPRD ID		13400	15475
Ensembl ID		ENSG00000139737	ENSG00000065491
Uniprot IDs		A0A0A0MSS3 A0A994J5K0 B7Z326 Q5T6P1 Q7L0J2 Q8ND83	Q9NU19
PDB IDs			6D0S
Enriched GO Terms of Interacting Partners?		Protein Binding Microtubule Organizing Center MRNA Splicing, Via Spliceosome Mitotic Spindle Astral Microtubule End MRNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Binding Identical Protein Binding Cytoskeleton Organization RNA Splicing Microtubule-based Process Cytoplasmic Stress Granule Membraneless Organelle Assembly RNA Processing Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Microtubule Cytoskeleton Organization Sperm Flagellum Regulation Of MRNA Processing Cytoplasm Nucleus Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Podosome Assembly Microtubule Binding Protein Localization To Microtubule Regulation Of Microtubule Polymerization Regulation Of Microtubule-based Process	Cytoskeleton Identical Protein Binding Cytoplasm Protein Binding Microtubule Binding Organelle Organization Regulation Of Autophagy Trans-Golgi Network Membrane Positive Regulation Of Autophagy Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Golgi Organization Microtubule-based Process Centriole Replication Cytoskeleton Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Microtubule Nucleation Microtubule De Novo Centriole Assembly Centriole Assembly Microtubule Organizing Center Organization Signaling Receptor Complex Adaptor Activity Supramolecular Fiber Organization Establishment Of Protein Localization Golgi Apparatus Cytosol Positive Regulation Of Long-term Neuronal Synaptic Plasticity Cellular Localization Positive Regulation Of Catabolic Process Microtubule Cytoskeleton Organization Protein Transport
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