DTNBP1 and NBEA

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		DTNBP1	NBEA
Gene Name		dystrobrevin binding protein 1	neurobeachin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Postsynaptic Density Sarcoplasm Cell Junction Axon Growth Cone Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane	Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Extrinsic Component Of Membrane
	Molecular Function	Protein Binding	Phospholipid Binding Protein Kinase Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Melanosome Organization Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Membrane Organization	Protein Localization Endosomal Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		53 interactors: ABI3 AKAP6 ARFIP2 BLOC1S5 BLOC1S6 BRF1 BRK1 C19orf66 CCDC146 CCDC153 CCDC53 CCHCR1 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 EXOC4 EXOC7 GLTSCR1L HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 MACF1 NBEA NDN NUF2 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SNAPIN SRGAP3 SSC5D SYBU SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM32 TRIM9 TXLNB ZNF490	5 interactors: BMPR2 DTNBP1 PRKAR2A PRKAR2B STRN4
Entrez ID		84062	26960
HPRD ID		06190	05352
Ensembl ID		ENSG00000047579	ENSG00000172915
Uniprot IDs		D6RJC6 Q96EV8	B3KXQ8 Q8NFP9
PDB IDs			1MI1
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Movement Of Cell Or Subcellular Component Cellular Pigmentation Cellular Localization Endosomal Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Organelle Organization Intracellular Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Organelle Localization Microtubule-based Process Vesicle-mediated Transport Microtubule-based Movement Establishment Of Vesicle Localization Establishment Of Organelle Localization Pigmentation Vesicle Localization Protein Localization Protein Transport Anterograde Synaptic Vesicle Transport Establishment Of Protein Localization Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Exocytosis Secretion By Cell Cell Projection Organization Synaptic Vesicle Transport Positive Regulation Of Cell Growth Endosome To Melanosome Transport Pigment Granule Maturation Axon Cargo Transport Small GTPase Mediated Signal Transduction Secretion Synaptic Vesicle Exocytosis Cellular Pigment Accumulation Nervous System Development Regulation Of Calcineurin-NFAT Signaling Cascade Cytoplasmic Transport Transport Positive Regulation Of Pigment Cell Differentiation Mitotic Nuclear Division Neuron Development Positive Regulation Of Developmental Pigmentation Negative Regulation Of Viral Release From Host Cell Generation Of Neurons	Negative Regulation Of CAMP-dependent Protein Kinase Activity Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Protein Kinase A Activity Renal Water Homeostasis Cellular Response To Glucagon Stimulus Water Transport Fluid Transport Activation Of Phospholipase C Activity Multicellular Organismal Water Homeostasis Response To Glucagon Blood Coagulation Positive Regulation Of Phospholipase C Activity Hemostasis Water Homeostasis Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Body Fluid Levels Wound Healing Renal System Process Regulation Of Secretion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Positive Regulation Of Protein Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Energy Reserve Metabolic Process Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation Positive Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Vasoconstriction Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Insulin Secretion Regulation Of Cellular Localization Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Protein Kinase Activity Regulation Of Peptide Hormone Secretion Regulation Of Protein Phosphorylation Neurotrophin Signaling Pathway Negative Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Hormone Secretion Positive Regulation Of Protein Metabolic Process Activation Of Protein Kinase Activity Regulation Of Signaling
Tagcloud ?		additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Difference) ?		additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Intersection) ?