CLIC2 and TRAPPC2

Number of citations of the paper that reports this interaction (PubMedID 12681486)
0

Data Source:
HPRD (in vivo)

		CLIC2	TRAPPC2
Description		chloride intracellular channel 2	trafficking protein particle complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Monoatomic Ion Channel Complex Chloride Channel Complex	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Chloride Channel Activity Protein Binding Oxidoreductase Activity	Protein Binding Transmembrane Transporter Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Signal Transduction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Monoatomic Ion Transmembrane Transport Cellular Oxidant Detoxification Chloride Transmembrane Transport	Skeletal System Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering
Pathways		Stimuli-sensing channels Ion homeostasis	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Spondyloepiphyseal dysplasia tarda
GWAS
Interacting Genes		4 interacting genes: NEDD4 NEDD4L TPRN TRAPPC2	34 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 KCTD1 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 SNCA TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBTB38 ZNF438 ZNF655 ZRANB1
Entrez ID		1193	6399
HPRD ID		02139	02189
Ensembl ID		ENSG00000155962	ENSG00000196459
Uniprot IDs		O15247	P0DI81 P0DI82 Q6IBE5
PDB IDs		2PER 2R4V 2R5G
Enriched GO Terms of Interacting Partners?		Sodium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Transmembrane Transporter Binding Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Negative Regulation Of Sodium Ion Transport Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Neuromuscular Junction Development Receptor Metabolic Process Protein Monoubiquitination Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Neuron Projection Development Receptor Internalization Regulation Of Dendrite Morphogenesis Negative Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Cellular Response To UV Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Neuron Projection Development Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Formation Of Structure Involved In A Symbiotic Process Regulation Of Dendrite Development Negative Regulation Of Monoatomic Ion Transport Cellular Response To Light Stimulus Negative Regulation Of Transmembrane Transport Regulation Of Plasma Membrane Bounded Cell Projection Organization Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Regulation Of Cell Projection Organization Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Regulation Of Nucleocytoplasmic Transport Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Channel Inhibitor Activity Nucleoplasm Positive Regulation Of Intracellular Transport N-terminal Peptidyl-lysine Acetylation	TRAPP Complex Vesicle Tethering TRAPPII Protein Complex Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity COPII Vesicle Coating Golgi Vesicle Transport Protein Binding Cis-Golgi Network Membrane Vesicle-mediated Transport Vesicle Organization Intracellular Transport Establishment Of Localization In Cell
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