CIDEC and UFSP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIDEC	UFSP1
Description		cell death inducing DFFA like effector c	UFM1 specific peptidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lipid Droplet Cytosol	Cytoplasm Cytosol
	Molecular Function	Protein Binding Phosphatidic Acid Binding Lipid Transfer Activity Molecular Condensate Scaffold Activity	Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity DeUFMylase Activity
	Biological Process	Lipid Transport Apoptotic Process Lipid Storage Lipid Droplet Organization Negative Regulation Of Lipid Catabolic Process Negative Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion	Proteolysis Protein Maturation Protein Ufmylation
Pathways		Lipid particle organization MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Resting heart rate ( 20639392 27798624 29769521)
Interacting Genes		7 interacting genes: CIDEA KLHL20 METTL15 NR0B2 SPATA12 UFSP1 ZBTB42	43 interacting genes: C10orf55 CIDEB CIDEC COG6 CREB5 CSTF2 FAM222B FANCL FOXH1 FOXI1 GLYCTK GPSM3 HNF1B HOXC9 HSF4 INCA1 KRTAP15-1 LASP1 MSRB3 MYOZ3 PITX1 PITX2 POGZ POU6F2 PROP1 PRR22 RAPGEF3 RBM14 RBPMS2 RUSC1 SMARCC1 SNRPC SPG21 TBX3 TCF7L2 TLX3 UBQLN2 VAC14 VAX2 VGLL3 VPS37C WWOX ZIC1
Entrez ID		63924	402682
HPRD ID		13060	18630
Ensembl ID		ENSG00000187288	ENSG00000176125
Uniprot IDs		A0A0A0MRY9 Q96AQ7	A0AAR1ZLH9 Q6NVU6
PDB IDs
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Factor Activity Chromatin Embryonic Morphogenesis DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Animal Organ Morphogenesis Pattern Specification Process Hepatoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryonic Digestive Tract Morphogenesis Embryonic Organ Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Myoblast Fate Commitment DNA Binding Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process System Development Transcription Regulator Complex Central Nervous System Development Somatotropin Secreting Cell Differentiation Regulation Of Primary Metabolic Process Embryonic Hindlimb Morphogenesis Regionalization Gland Development Pituitary Gland Development Lipid Droplet Fusion Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Hindlimb Morphogenesis Nucleus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Transcription Cis-regulatory Region Binding Inner Ear Morphogenesis Outflow Tract Morphogenesis Lipid Transfer Activity Regulation Of Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Gene Expression Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Axis Specification
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