CHRNA1 and CHRND

Number of citations of the paper that reports this interaction (PMID 7695910)
11

Data Source:
HPRD (in vitro)

		CHRNA1	CHRND
Gene Name		cholinergic receptor, nicotinic, alpha 1 (muscle)	cholinergic receptor, nicotinic, delta (muscle)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Cell Junction Neuromuscular Junction Postsynaptic Membrane	Plasma Membrane Acetylcholine-gated Channel Complex Cell Junction Postsynaptic Membrane
	Molecular Function	Acetylcholine-activated Cation-selective Channel Activity Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine Binding	Acetylcholine-activated Cation-selective Channel Activity Acetylcholine Binding
	Biological Process	Skeletal Muscle Contraction Transport Signal Transduction Synaptic Transmission Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Musculoskeletal Movement Neuromuscular Process Neuron Cellular Homeostasis Cation Transmembrane Transport	Skeletal Muscle Contraction Transport Muscle Contraction Signal Transduction Synaptic Transmission Regulation Of Membrane Potential Skeletal Muscle Tissue Growth Musculoskeletal Movement Neuromuscular Process Cation Transmembrane Transport
Pathways		Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Acetylcholine Binding And Downstream Events Activation of Nicotinic Acetylcholine Receptors Postsynaptic nicotinic acetylcholine receptors Presynaptic nicotinic acetylcholine receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Highly calcium permeable nicotinic acetylcholine receptors Transmission across Chemical Synapses	Acetylcholine Binding And Downstream Events Postsynaptic nicotinic acetylcholine receptors Activation of Nicotinic Acetylcholine Receptors Presynaptic nicotinic acetylcholine receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Highly sodium permeable acetylcholine nicotinic receptors Transmission across Chemical Synapses
Drugs
Diseases
GWAS			Brain lesion load ( 19010793)
Protein-Protein Interactions		4 interactors: CHRND CHRNE CHRNG ITGA7	2 interactors: CHRNA1 GRB2
Entrez ID		1134	1144
HPRD ID		00007	01516
Ensembl ID		ENSG00000138435
Uniprot IDs		P02708 Q53SH4	Q07001
PDB IDs		1Y5P 1Y5T 1Y6C
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Regulation Of Membrane Potential Synaptic Transmission Skeletal Muscle Tissue Development Cell-cell Signaling Skeletal Muscle Organ Development Cation Transmembrane Transport Skeletal Muscle Tissue Growth Cation Transport Ion Transmembrane Transport Muscle Organ Development Striated Muscle Tissue Development Muscle Tissue Development Transmembrane Transport Ion Transport Synaptic Transmission, Cholinergic Signal Transduction Muscle Structure Development Signaling Cell Communication Heterotypic Cell-cell Adhesion Skeletal Muscle Contraction Cellular Response To Stimulus Endodermal Cell Differentiation Musculoskeletal Movement Endoderm Formation Striated Muscle Contraction Response To Stimulus Endoderm Development Integrin-mediated Signaling Pathway Neuromuscular Process Formation Of Primary Germ Layer Regulation Of Cell Shape Cell-matrix Adhesion Tissue Development	Skeletal Muscle Tissue Growth
Tagcloud ?		ags aire autoimmune autoimmunity copies ds dysregulation euploid fundamental gad1 graves hypothyroidism intrathymic klk3 owing pge plp1 predisposition promiscuous restricted sag strikingly thymus thymuses thyroglobulin thyroiditis tolerance trisomy typically	acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 gp1ba justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Difference) ?		ags aire autoimmune autoimmunity copies ds dysregulation euploid fundamental gad1 graves hypothyroidism intrathymic klk3 owing pge plp1 predisposition promiscuous restricted sag strikingly thymus thymuses thyroglobulin thyroiditis tolerance trisomy typically	acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 gp1ba justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Intersection) ?