GLCCI1 and VPS28

Number of citations of the paper that reports this interaction (PMID 11591653)
37

Data Source:
HPRD (in vivo, in vitro)

		GLCCI1	VPS28
Gene Name		glucocorticoid induced transcript 1	vacuolar protein sorting 28 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	ESCRT I Complex Cytoplasm Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Protein Complex Binding
	Biological Process		Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Negative Regulation Of Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Membrane Organization Intracellular Transport Of Virus
Pathways			Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: VPS28	27 interactors: ASF1A BLZF1 CARD9 CBX5 FABP3 FAM154A GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SKIL SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 USHBP1 VPS37A VPS37B VPS37C VPS52
Entrez ID		113263	51160
HPRD ID		17043	11675
Ensembl ID		ENSG00000106415	ENSG00000160948
Uniprot IDs		Q86VQ1	Q548N1 Q9UK41
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Transport Via Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Protein Processing Protein Targeting To Vacuole Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Intracellular Transport Of Virus Vacuolar Transport Negative Regulation Of Protein Ubiquitination Viral Life Cycle Regulation Of Protein Ubiquitination Endosomal Transport Protein Processing Establishment Of Protein Localization To Organelle	Virion Assembly Viral Protein Processing Intracellular Transport Of Virus Viral Life Cycle Protein Transport Endosomal Transport Establishment Of Protein Localization Viral Process Protein Localization Membrane Organization Protein Processing Intracellular Transport Regulation Of Extracellular Vesicular Exosome Assembly Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Establishment Of Localization In Cell Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Gene Expression Negative Regulation Of Transferase Activity Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Localization Cell Cycle Arrest Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Protein Trimerization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Embryonic Digestive Tract Development Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Negative Regulation Of Protein Kinase Activity DNA-templated Transcription, Initiation Transport Negative Regulation Of Gene Expression Muscle Structure Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Kinase Activity Cell Cycle Positive Regulation Of Lipid Biosynthetic Process Glycogen Metabolic Process
Tagcloud ?		antisense assayed biklf combinations coordination embryos erythroid gata gata1 gata2 greatly hematopoiesis hematopoietic identifies kelch kiaa0650 krcp maturation mesoderm morpholinos posterior precise precursors scl sought specification testhymin zebrafish	advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Difference) ?		antisense assayed biklf combinations coordination embryos erythroid gata gata1 gata2 greatly hematopoiesis hematopoietic identifies kelch kiaa0650 krcp maturation mesoderm morpholinos posterior precise precursors scl sought specification testhymin zebrafish	advancement cd connected counterscreen crohn encodes endosomal immortalized initiating irrespective multidomain nod2 proinflammatory regulators relapsing resource revealing reveals screen secretion sensor sorting strongest subnetworks tnfalpha usp8 validate valuable vesicle
Tagcloud (Intersection) ?