ADCY7 and BUD31

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADCY7	BUD31
Gene Name		adenylate cyclase 7	BUD31 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Spliceosomal Complex
	Molecular Function	Adenylate Cyclase Activity ATP Binding Metal Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Renal Water Homeostasis Energy Reserve Metabolic Process CAMP Biosynthetic Process Water Transport Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Synaptic Transmission Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Activation Of Protein Kinase A Activity Intracellular Signal Transduction Small Molecule Metabolic Process Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Transmembrane Transport Maternal Process Involved In Female Pregnancy Cellular Response To Ethanol Cellular Response To Glucagon Stimulus	MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Signaling by GPCR Ca-dependent events CaM pathway Hedgehog 'off' state Phospholipase C-mediated cascade Signaling by FGFR in disease Integration of energy metabolism Activation of GABAB receptors G alpha (s) signalling events Signaling by EGFRvIII in Cancer Adenylate cyclase activating pathway PLCG1 events in ERBB2 signaling DAP12 signaling G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Glucagon signaling in metabolic regulation Signaling by PDGF Calmodulin induced events DAP12 interactions PKA-mediated phosphorylation of CREB Opioid Signalling PKA activation Aquaporin-mediated transport EGFR interacts with phospholipase C-gamma Signaling by ERBB2 Signaling by EGFR PKA-mediated phosphorylation of CREB GPCR downstream signaling Calmodulin induced events Downstream signal transduction Signaling by EGFR in Cancer PKA activation Transmission across Chemical Synapses DAG and IP3 signaling CaM pathway Downstream signaling of activated FGFR Innate Immune System GABA B receptor activation GABA receptor activation Adenylate cyclase inhibitory pathway PKA activation in glucagon signalling Signalling by NGF PLC beta mediated events Vasopressin regulates renal water homeostasis via Aquaporins Signaling by Ligand-Responsive EGFR Variants in Cancer G-protein mediated events NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR Inhibition of adenylate cyclase pathway Adenylate cyclase inhibitory pathway Signaling by Hedgehog PLC-gamma1 signalling
Drugs
Diseases
GWAS		Crohn's disease ( 23128233)
Protein-Protein Interactions		4 interactors: BUD31 PLSCR1 PRKCD XRCC6	7 interactors: ADCY7 APP BEND5 CTNNBL1 KRTAP10-3 KRTAP10-7 RELB
Entrez ID		113	8896
HPRD ID		02663	10351
Ensembl ID		ENSG00000121281	ENSG00000106245
Uniprot IDs		F5H4D1 P51828	B7Z4S9 P41223
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Platelet Activation Gene Expression Interleukin-10 Production Cellular Hyperosmotic Salinity Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Filopodium Assembly Defense Response Interleukin-12 Production Cellular Response To X-ray Positive Regulation Of Ceramide Biosynthetic Process Phosphatidylserine Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Establishment Of Integrated Proviral Latency Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Cellular Hyperosmotic Response Hyperosmotic Salinity Response Positive Regulation Of Superoxide Anion Generation Establishment Of Viral Latency Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Phospholipid Scrambling Blood Coagulation Regulation Of Gene Expression Hemostasis Cellular Response To Salt Stress Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Activation Regulation Of Superoxide Anion Generation DNA Ligation Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Immune System Process Response To Interferon-beta Positive Regulation Of Protein Dephosphorylation Regulation Of Body Fluid Levels Double-strand Break Repair Via Nonhomologous End Joining Neutrophil Activation Wound Healing Hyperosmotic Response Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Immune Response Positive Regulation Of Lipid Catabolic Process Phosphatidylserine Metabolic Process	Immune System Process Innate Immune Response Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Immune Response Defense Response Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Neuron Remodeling Cellular Response To Ethanol Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process Activation Of Protein Kinase A Activity T-helper 1 Cell Differentiation MRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis CAMP Biosynthetic Process RNA Processing Regulation Of Body Fluid Levels Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Myeloid Dendritic Cell Differentiation Myeloid Dendritic Cell Activation T-helper 1 Type Immune Response Positive Regulation Of Cellular Metabolic Process Cell Activation Renal Water Homeostasis T-helper Cell Differentiation Cellular Response To Osmotic Stress Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Immune System Development Regulation Of Protein Kinase Activity Mating Behavior CAMP Metabolic Process Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Regulation Of Kinase Activity Somatic Diversification Of Immunoglobulins Cellular Response To Glucagon Stimulus
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