ADCY7

Description		adenylate cyclase 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Adenylate Cyclase Activity ATP Binding Lyase Activity Phosphorus-oxygen Lyase Activity Metal Ion Binding
	Biological Process	Regulation Of Adaptive Immune Response CAMP Biosynthetic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cyclic Nucleotide Biosynthetic Process Intracellular Signal Transduction Maternal Process Involved In Female Pregnancy Cellular Response To Lithium Ion Cellular Response To Ethanol Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state GPER1 signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs		Colforsin
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Crohn's disease ( 23128233) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Ulcerative colitis ( 28067908 28067910)
Interacting Genes		4 interacting genes: BUD31 PLSCR1 PRKCD XRCC6
Entrez ID		113
HPRD ID		02663
Ensembl ID		ENSG00000121281
Uniprot IDs		B3KSJ0 F5H4D1 P51828 Q86YI0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Catalytic Activity Positive Regulation Of Immune Response Positive Regulation Of Biosynthetic Process Regulation Of Immune Response DNA End Binding Regulation Of Defense Response Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Catalytic Activity Cellular Response To Radiation Ku70:Ku80 Complex Regulation Of Cell Activation Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Phospholipid Scramblase Activity Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Endodeoxyribonuclease Activity Termination Of Signal Transduction Positive Regulation Of Immune System Process Negative Regulation Of Filopodium Assembly Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Deoxyribonuclease Activity Protein Kinase C Signaling Response To Other Organism Positive Regulation Of Macromolecule Metabolic Process Cellular Hyperosmotic Salinity Response DNA-dependent Protein Kinase Complex Positive Regulation Of Metabolic Process Hyperosmotic Salinity Response Defense Response Nuclear Telomere Cap Complex Positive Regulation Of Phosphate Metabolic Process DNA-dependent Protein Kinase-DNA Ligase 4 Complex Regulation Of RNA Metabolic Process Response To External Biotic Stimulus 5'-deoxyribose-5-phosphate Lyase Activity Positive Regulation Of Innate Immune Response Cellular Response To Chemical Stress Double-stranded Telomeric DNA Binding Nonhomologous End Joining Complex CD4 Receptor Binding Phospholipase C/protein Kinase C Signal Transduction Cellular Response To Hydroperoxide Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Endodeoxyribonuclease Activity
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