CYTOR and RBBP7

Number of citations of the paper that reports this interaction (PubMedID 15451426)
0

Data Source:
HPRD (in vivo)

		CYTOR	RBBP7
Description		cytoskeleton regulator RNA	RB binding protein 7, chromatin remodeling factor
Image		No pdb structure
GO Annotations	Cellular Component		Histone Deacetylase Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol NuRD Complex NURF Complex ESC/E(Z) Complex Sin3-type Complex ATPase Complex
	Molecular Function		RNA Binding Protein Binding Histone Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Brain Development Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Response To Steroid Hormone Cellular Heat Acclimation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways			PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS Defective pyroptosis Negative Regulation of CDH1 Gene Transcription Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		14 interacting genes: BANP BRMS1 BRMS1L HDAC1 HDAC2 HSD17B14 ING1 RBBP4 RBBP7 RBP1 SAP30 SIN3A TRIM55 TRIM63	32 interacting genes: APPL1 APPL2 BRCA1 BRMS1 BRMS1L BUB3 CREBBP CRYAA CYTOR DDB1 DHX30 ERCC6 ESR1 H3-4 H3C1 H4C1 HDAC1 HDAC2 ING1 MBD3 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1
Entrez ID		112597	5931
HPRD ID		14654	04231
Ensembl ID		ENSG00000222041	ENSG00000102054
Uniprot IDs			Q16576 Q6FHQ0
PDB IDs			3CFS 3CFV 7M3X
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone Deacetylase Complex Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion NuRD Complex Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Fate Specification Negative Regulation Of Developmental Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Nucleobase-containing Compound Metabolic Process Histone Deacetylase Binding Regulation Of Cell Fate Commitment Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Developmental Process ESC/E(Z) Complex Negative Regulation Of Signal Transduction Negative Regulation Of RNA Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Stem Cell Differentiation Positive Regulation Of Multicellular Organismal Process Chromatin Organization Protein Lysine Delactylase Activity Fungiform Papilla Formation NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Nucleosomal DNA Binding Hair Follicle Placode Formation Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Biosynthetic Process Cellular Response To Dopamine NURF Complex Regulation Of Signal Transduction Response To Dopamine	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Chromatin Remodeling Chromatin Organization Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Nucleus Negative Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Epigenetic Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process NuRD Complex Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Histone Deacetylase Complex Regulation Of Gene Expression Negative Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Specification Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Rhythmic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Developmental Process Histone Deacetylase Binding Negative Regulation Of Developmental Process Protein-containing Complex Heterochromatin Formation Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Nucleosomal DNA Binding Chromatin Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Fate Commitment Negative Regulation Of Gene Expression, Epigenetic Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Migration Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process
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