GTF3C6 and SPATC1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GTF3C6	SPATC1L
Description		general transcription factor IIIC subunit 6	spermatogenesis and centriole associated 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nuclear Body	Cytoplasm Centrosome Sperm Head-tail Coupling Apparatus
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	Spermatogenesis Actin Polymerization Or Depolymerization Positive Regulation Of CAMP/PKA Signal Transduction
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		2 interacting genes: APP SPATC1L	51 interacting genes: ACOT7 ARL4A ARMC7 ATPAF2 CABP2 CLTC DISC1 EXOSC8 FOXN1 FSD2 GOLGA6A GTF3C6 HOOK2 IKZF1 KIFC3 KRT40 KRTAP5-9 LZTS2 MISP MTUS2 MYO15B NCK2 NUTF2 NXF1 PARN PHC2 PHF11 PIAS2 PICK1 PINK1 PLEC PNMA1 POLR1C PPP1CB PPP1CC QARS1 RAD51D RBMY1F RBMY1J REL SIAH1 SNRNP70 SYCE1 TCF4 TEKT4 TRIM27 TRMO TSR2 UBL5 ZBTB4 ZBTB8B
Entrez ID		112495	84221
HPRD ID		12886	10753
Ensembl ID		ENSG00000155115	ENSG00000160284
Uniprot IDs		Q969F1	Q9H0A9
PDB IDs		8CLK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of CAMP/PKA Signal Transduction Regulation Of CAMP/PKA Signal Transduction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Alpha DNA Polymerase:primase Complex DNA/RNA Hybrid Binding Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway DNA Replication, Synthesis Of Primer Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding	Protein Binding Cytoskeleton Identical Protein Binding Nucleus RNA Metabolic Process PTW/PP1 Phosphatase Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing
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