ERLIN2 and CCT2

Number of citations of the paper that reports this interaction (PMID 23190606)
1

Data Source:
BioGRID (pull down)

		ERLIN2	CCT2
Gene Name		ER lipid raft associated 2	chaperonin containing TCP1, subunit 2 (beta)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein Complex Extracellular Vesicular Exosome	Zona Pellucida Receptor Complex Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Unfolded Protein Binding
	Biological Process	ER-associated Ubiquitin-dependent Protein Catabolic Process	Protein Folding Binding Of Sperm To Zona Pellucida Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Chaperone-mediated Protein Complex Assembly Toxin Transport
Pathways			Cargo trafficking to the periciliary membrane Protein folding Organelle biogenesis and maintenance Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Association of TriC/CCT with target proteins during biosynthesis Chaperonin-mediated protein folding Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		1 interactors: CCT2	18 interactors: ACTA1 ACTB EEF2 ERLIN2 FCHSD2 HSP90AB1 HSP90B1 PRPF40A PSMC6 PSMD2 RPS3 SSSCA1 SUMO4 TUBA1B TUBB VAV2 VRK2 YWHAG
Entrez ID		11160	10576
HPRD ID		15437	06895
Ensembl ID		ENSG00000147475	ENSG00000166226
Uniprot IDs		O94905	P78371
PDB IDs
Enriched GO Terms of Interacting Partners?		Chaperone-mediated Protein Complex Assembly Toxin Transport Binding Of Sperm To Zona Pellucida Sperm-egg Recognition 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell-cell Recognition Cell Recognition Single Fertilization Fertilization Protein Folding Cellular Protein Complex Assembly	Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Division Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cellular Protein Metabolic Process Cell Cycle Phase Transition Positive Regulation Of Transferase Activity Regulation Of Apoptotic Process Protein Folding Immune System Process Regulation Of Cell Death Cell Cycle Process Endocytosis Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Innate Immune Response Fc Receptor Mediated Stimulatory Signaling Pathway Response To Stress Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Immune Response-regulating Signaling Pathway Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Interleukin-4 Modification-dependent Protein Catabolic Process Movement Of Cell Or Subcellular Component Cellular Response To Stress Apoptotic Process Regulation Of Protein Metabolic Process Positive Regulation Of Catalytic Activity Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Programmed Cell Death Response To Interleukin-4 Cellular Protein Catabolic Process Cell Death Death Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Catalytic Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of DNA N-glycosylase Activity Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint 'de Novo' Posttranslational Protein Folding Protein Catabolic Process Phagocytosis
Tagcloud ?		8p11 adaptation advantage amplicon assayed cancerous carcinogenesis confer coordinates cytoprotective expresses facilitated facilitating ire1alpha knocked luminal mcf10a nontransformed oncogenes oncogenesis plenti6 protecting raft sensor sheds stably stresses v5 xbp1	antral atresia atretic bga build categorized cattle cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis tgm2 transcriptomic ultimately
Tagcloud (Difference) ?		8p11 adaptation advantage amplicon assayed cancerous carcinogenesis confer coordinates cytoprotective expresses facilitated facilitating ire1alpha knocked luminal mcf10a nontransformed oncogenes oncogenesis plenti6 protecting raft sensor sheds stably stresses v5 xbp1	antral atresia atretic bga build categorized cattle cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis tgm2 transcriptomic ultimately
Tagcloud (Intersection) ?