ERLIN2

Description		ER lipid raft associated 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Protein-containing Complex Membrane Raft
	Molecular Function	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding
	Biological Process	Lipid Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process SREBP Signaling Pathway ERAD Pathway Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process
Pathways		ABC-family proteins mediated transport Signaling by FGFR1 in disease Defective CFTR causes cystic fibrosis Signaling by plasma membrane FGFR1 fusions AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Axial length ( 24144296)
Interacting Genes		1 interacting genes: CCT2
Entrez ID		11160
HPRD ID		15437
Ensembl ID		ENSG00000147475
Uniprot IDs		A0A384ME54 O94905
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Protein Localization To Cajal Body Zona Pellucida Receptor Complex ScaRNA Localization To Cajal Body Regulation Of Telomerase RNA Localization To Cajal Body Chaperonin-containing T-complex Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening RNA Localization Binding Of Sperm To Zona Pellucida ATP-dependent Protein Folding Chaperone Sperm-egg Recognition Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Cell-cell Recognition Positive Regulation Of Telomere Maintenance Azurophil Granule Lumen Cell Body Regulation Of DNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Unfolded Protein Binding Cell Recognition Regulation Of Protein Localization To Nucleus Protein Folding Protein Stabilization Regulation Of Chromosome Organization Positive Regulation Of DNA Metabolic Process Ubiquitin Protein Ligase Binding Microtubule Regulation Of Protein Stability ATP Hydrolysis Activity
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