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EMILIN1 and LAIR2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
EMILIN1
LAIR2
Description
elastin microfibril interfacer 1
leukocyte associated immunoglobulin like receptor 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Extracellular Space
Extracellular Matrix
Integrin Alpha4-beta1 Complex
Extracellular Exosome
EMILIN Complex
Extracellular Region
Plasma Membrane
Molecular Function
Extracellular Matrix Structural Constituent
Protein Binding
Extracellular Matrix Constituent Conferring Elasticity
Identical Protein Binding
Molecular Adaptor Activity
Integrin Binding Involved In Cell-matrix Adhesion
Protein Binding
Biological Process
Aortic Valve Morphogenesis
Cell Adhesion
Cell-matrix Adhesion
Regulation Of Blood Pressure
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Cell Migration
Negative Regulation Of Angiogenesis
Positive Regulation Of Blood Coagulation
Extracellular Matrix Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of Collagen Biosynthetic Process
Cell Adhesion Mediated By Integrin
Regulation Of Cell Population Proliferation
Positive Regulation Of Apoptotic Process
Positive Regulation Of Angiogenesis
Elastic Fiber Assembly
Negative Regulation Of Cell Activation
Negative Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Defense Response To Bacterium
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Positive Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Platelet Aggregation
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Macrophage Migration
Immune Response-regulating Signaling Pathway
Pathways
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Neurological blood protein biomarker levels (
31320639
)
Interacting Genes
28 interacting genes:
ABI3
BEX3
BEX5
BFSP1
CDCA8
CENPQ
COG7
DYNC1I1
EMILIN2
FBXO28
GNG13
IFT20
LAIR2
LRRIQ1
MIA2
MTMR9
NECAB2
NMI
PLAC9
PRKAA2
RABGEF1
RIBC1
SNAPC5
TAB2
TSNAX
YJU2
ZC2HC1C
ZNF655
5 interacting genes:
EMILIN1
LCN2
SGTA
UBQLN1
UBQLN2
Entrez ID
11117
3904
HPRD ID
00563
04293
Ensembl ID
ENSG00000138080
ENSG00000167618
Uniprot IDs
Q9Y6C2
Q6ISS4
PDB IDs
2KA3
2OII
Enriched GO Terms of Interacting Partners
?
A2A Adenosine Receptor Binding
Positive Regulation Of ERAD Pathway
Regulation Of ERAD Pathway
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Response To Endoplasmic Reticulum Stress
ERAD Pathway
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
Identical Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Regulation Of Protein Catabolic Process
Regulation Of Proteolysis
Positive Regulation Of Hippocampal Neuron Apoptotic Process
Autophagosome
Negative Regulation Of Store-operated Calcium Channel Activity
Proteasomal Protein Catabolic Process
Positive Regulation Of Iron Ion Import Across Plasma Membrane
Enterobactin Binding
Positive Regulation Of Endothelial Tube Morphogenesis
Iron Ion Sequestering Activity
Regulation Of Cellular Response To Stress
TRC Complex
Positive Regulation Of Catabolic Process
EMILIN Complex
Autophagosome Organization
Autophagosome Assembly
Negative Regulation Of G Protein-coupled Receptor Internalization
Positive Regulation Of Macromolecule Metabolic Process
Cellular Response To Decreased Oxygen Levels
Siderophore Transport
Cellular Response To Hypoxia
Cellular Response To Stress
Protein Catabolic Process
Integrin Alpha4-beta1 Complex
Negative Regulation Of Collagen Fibril Organization
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Proteolysis Involved In Protein Catabolic Process
Cellular Response To Oxygen Levels
Cytoplasmic Vesicle Lumen
Negative Regulation Of Hippocampal Neuron Apoptotic Process
Response To Kainic Acid
BAT3 Complex Binding
Negative Regulation Of Clathrin-dependent Endocytosis
Vacuole Organization
Response To Herbicide
Positive Regulation Of Metabolic Process
Regulation Of Hippocampal Neuron Apoptotic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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