VAX1 and SPANXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VAX1	SPANXN2
Description		ventral anterior homeobox 1	SPANX family member N2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Axon Guidance Central Nervous System Development Brain Development Glial Cell Differentiation Neuron Differentiation Skeletal Muscle Cell Differentiation Camera-type Eye Development Astrocyte Differentiation Roof Of Mouth Development Neuroepithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Orofacial clefts ( 20023658)
Interacting Genes		14 interacting genes: DVL3 EAF1 ESRRG HECW1 HMBOX1 MLLT3 PICK1 POLR3C PSMB1 RCOR3 RPRD1B SDCBP2 SPANXN2 USP20	50 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BIVM CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A GPRASP3 H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84
Entrez ID		11023	494119
HPRD ID		16052	18091
Ensembl ID		ENSG00000148704	ENSG00000268988
Uniprot IDs		Q5SQQ9	Q5MJ10
PDB IDs
Enriched GO Terms of Interacting Partners?			Nucleus DNA Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly SMN-Sm Protein Complex Nucleoplasm Protein-RNA Complex Assembly Zinc Ion Binding Sequence-specific DNA Binding SMN Complex Gemini Of Cajal Bodies Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?