SLC26A1 and ST6GAL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC26A1	ST6GAL2
Description		solute carrier family 26 member 1	ST6 beta-galactoside alpha-2,6-sialyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Solute:inorganic Anion Antiporter Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Antiporter Activity Sulfate:bicarbonate Antiporter Activity Oxalate Transmembrane Transporter Activity Chloride:bicarbonate Antiporter Activity	Beta-galactoside Alpha-2,6-sialyltransferase Activity Protein Binding Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport Bicarbonate Transport Oxalate Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Sulfate Transmembrane Transport Chloride Transmembrane Transport	Carbohydrate Metabolic Process Protein Glycosylation Oligosaccharide Metabolic Process Sialylation
Pathways		Transport and metabolism of PAPS Inorganic anion exchange by SLC26 transporters	Sialic acid metabolism
Drugs
Diseases
GWAS		A body shape index ( 34021172) Limited cutaneous systemic scleroderma ( 29293537) Polymyositis ( 26362759) Systemic sclerosis ( 29293537) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum immune biomarker levels ( 32066700)
Interacting Genes		2 interacting genes: RHOU ST6GAL2	16 interacting genes: AQP6 CD53 CREB3 FNDC9 GIPC3 GOLM1 GPX8 HSD17B13 PGRMC2 PSCA SLC26A1 SLC39A2 SLC7A1 TIMMDC1 TMEM14B TMEM237
Entrez ID		10861	84620
HPRD ID		15361	12237
Ensembl ID		ENSG00000145217	ENSG00000144057
Uniprot IDs		Q9H2B4	Q96JF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Beta-galactoside Alpha-2,6-sialyltransferase Activity Golgi Membrane Positive Regulation Of Focal Adhesion Disassembly Sialylation Sialyltransferase Activity Rac Protein Signal Transduction Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Golgi Apparatus Podosome Positive Regulation Of Protein Targeting To Mitochondrion Oligosaccharide Metabolic Process Golgi Cisterna Membrane Regulation Of Cell-substrate Junction Organization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Establishment Of Cell Polarity
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