HBS1L and PELO

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HBS1L	PELO
Gene Name		HBS1-like translational GTPase	pelota homolog (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Translation Elongation Factor Activity GTPase Activity GTP Binding	Endonuclease Activity Metal Ion Binding
	Biological Process	Translation Translational Elongation Signal Transduction	Cell Cycle Cell Proliferation Chromosome Organization Cell Division Nuclear-transcribed MRNA Catabolic Process, Non-stop Decay Nuclear-transcribed MRNA Catabolic Process, No-go Decay RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) HbA2 levels ( 23043469) Hematocrit ( 19862010) Hematological and biochemical traits ( 20139978) Hematological parameters ( 19820697) Hematology traits ( 23263863 19853236) Mean corpuscular hemoglobin ( 23263863 20139978 19862010) Mean corpuscular hemoglobin concentration ( 23263863 20139978) Mean corpuscular volume ( 23263863 20139978 19862010) Mean platelet volume ( 22423221) Other erythrocyte phenotypes ( 19862010) Platelet counts ( 22139419 20139978) Red blood cell count ( 20139978) Red blood cell traits ( 20927387 23222517) White blood cell count ( 20139978) White blood cell types ( 21738478)	Presence of antiphospholipid antibodies ( 23509613) Response to platinum-based agents ( 22020760)
Protein-Protein Interactions		5 interactors: APP PELO SRPK1 SRPK2 UBE2G2	2 interactors: HBS1L PRMT6
Entrez ID		10767	53918
HPRD ID		06582	09309
Ensembl ID		ENSG00000112339
Uniprot IDs		D9YZV0 Q9Y450	Q9BRX2
PDB IDs			1X52
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Regulation Of MRNA Processing RNA Processing Regulation Of RNA Splicing Nuclear-transcribed MRNA Catabolic Process, Non-stop Decay Nuclear Speck Organization Nucleus Organization Innate Immune Response Synaptic Growth At Neuromuscular Junction Regulation Of Viral Process Collateral Sprouting In Absence Of Injury Nuclear-transcribed MRNA Catabolic Process, No-go Decay Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Cell Cycle Immune Response RNA Metabolic Process Cellular Protein Modification Process Protein Phosphorylation Defense Response RNA Surveillance Neuron Remodeling Sperm Chromatin Condensation RNA Splicing Cellular Copper Ion Homeostasis Phosphorylation Copper Ion Homeostasis Suckling Behavior Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Spermatid Nucleus Differentiation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Immune System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation	Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone H4-R3 Methylation Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation
Tagcloud ?		10p14 2p16 3p24 6q23 8q24 eomes eomesodermin european gwas gwass haematopoiesis hl hla hodgkin identifies inherited insight intergenic localizes loci mapping maps meta myb perform rs3806624 rs7745098 susceptibility totalling	acp1 adaptor attenuates attracting binds characterization composed deregulated dozen existence extensively hax1 inhibiting initiate interacting largely negatively p85 phosphatidylinositol pi3k plethora proteomic recruitment reveal signalling thereby transduction uncharacterized ywhaz
Tagcloud (Difference) ?		10p14 2p16 3p24 6q23 8q24 eomes eomesodermin european gwas gwass haematopoiesis hl hla hodgkin identifies inherited insight intergenic localizes loci mapping maps meta myb perform rs3806624 rs7745098 susceptibility totalling	acp1 adaptor attenuates attracting binds characterization composed deregulated dozen existence extensively hax1 inhibiting initiate interacting largely negatively p85 phosphatidylinositol pi3k plethora proteomic recruitment reveal signalling thereby transduction uncharacterized ywhaz
Tagcloud (Intersection) ?