NUP50 and KPNA5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NUP50	KPNA5
Gene Name		nucleoporin 50kDa	karyopherin alpha 5 (importin alpha 6)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytoplasm Nuclear Membrane	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein Transporter Activity
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Intracellular Transport MRNA Transport Transmembrane Transport	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport	ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS			Telomere length ( 21460395)
Protein-Protein Interactions		13 interactors: APP CDKN1B IPO13 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA6 KPNB1 RAN SRPK2 XPO1	7 interactors: ANP32A ANP32B BRMS1 CDKN1B IL32 NUP50 SPOPL
Entrez ID		10762	3841
HPRD ID		05226	05179
Ensembl ID		ENSG00000093000	ENSG00000196911
Uniprot IDs		Q9UKX7	O15131
PDB IDs		2EC1 3TJ3
Enriched GO Terms of Interacting Partners?		Protein Localization To Nucleus NLS-bearing Protein Import Into Nucleus Protein Import Into Nucleus Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Cytoplasmic Transport Protein Targeting Intracellular Protein Transport Intracellular Transport Of Virus Intracellular Transport Cellular Protein Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Cellular Localization Protein Localization Viral Life Cycle Cytokine-mediated Signaling Pathway Transport Viral Process Cellular Response To Cytokine Stimulus Ribosomal Small Subunit Export From Nucleus Response To Cytokine Cellular Response To Organic Substance Signal Transduction Cell Surface Receptor Signaling Pathway Signaling Ribosomal Large Subunit Export From Nucleus Cell Communication Ribosomal Subunit Export From Nucleus Response To Organic Substance Cellular Response To Stimulus Apoptotic DNA Fragmentation Apoptotic Nuclear Changes Protein Export From Nucleus Response To Stimulus Positive Regulation Of Cell Cycle Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Nuclear Speck Organization Regulation Of DNA Recombination Ribonucleoprotein Complex Biogenesis Execution Phase Of Apoptosis Synaptic Growth At Neuromuscular Junction Viral Penetration Into Host Nucleus DNA Catabolic Process, Endonucleolytic Regulation Of Cell Cycle	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Anoikis Inner Ear Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Autophagic Cell Death Ear Development Regulation Of Protein Metabolic Process Protein Processing Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus
Tagcloud ?		accompany als amyotrophic cytosolic degenerating deleterious deregulation disrupted dominantly drosophila elicited flies hey histopathologic inherited intercellular lifespan microarrays misregulation neurotoxicity notch nucleoporin paradigms paralysis signature spindleb tardbp tdp widespread	accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Difference) ?		accompany als amyotrophic cytosolic degenerating deleterious deregulation disrupted dominantly drosophila elicited flies hey histopathologic inherited intercellular lifespan microarrays misregulation neurotoxicity nucleoporin paradigms paralysis signature spindleb tardbp tdp widespread	accurately adam12 cancers candidate centb1 centg1 dip2c exome gli1 grin2d hdlbp hedgehog ikbkb infrequent involvement kb mutation nfkb1 notch1 otof pik3ca point prevalence recurring sequencing somatic strengthen substantial
Tagcloud (Intersection) ?		notch