ZNF576 and MAPKAPK5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZNF576	MAPKAPK5
Gene Name		zinc finger protein 576	mitogen-activated protein kinase-activated protein kinase 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding	P53 Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	MAPK Cascade Activation Of MAPK Activity Regulation Of Translation Signal Transduction Ras Protein Signal Transduction Negative Regulation Of TOR Signaling Protein Autophosphorylation Stress-induced Premature Senescence
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AES AP4B1 KRT15 MAPKAPK5 RARG SH3GLB1 SUOX	28 interactors: ATF2 CDCA8 EEF2K EIF4E EIF4EBP1 GYS1 HSPB1 HSPB2 JUN LSR MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK4 MAPK6 MAPK9 MBP MYH11 PLA2G4A RPL13 SRPK1 SRPK2 TAB1 TP53 ZNF282 ZNF576
Entrez ID		79177	8550
HPRD ID		15855	09467
Ensembl ID			ENSG00000089022
Uniprot IDs		Q9H609	Q8IW41
PDB IDs
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Positive Regulation Of Anoikis Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Growth Plate Cartilage Chondrocyte Differentiation	MAPK Cascade Signal Transduction By Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Intracellular Signal Transduction Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Phosphorylation Regulation Of Innate Immune Response Response To Organic Substance Response To Stress Gene Expression Cellular Response To Organic Substance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Protein Phosphorylation Signaling Phosphate-containing Compound Metabolic Process Cell Cycle Cell Communication Ras Protein Signal Transduction Innate Immune Response Signal Transduction Mitochondrion Organization Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Apoptotic Mitochondrial Changes Defense Response Response To Toxic Substance Cellular Response To Stimulus Response To Stimulus
Tagcloud ?			acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Difference) ?			acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Intersection) ?