EBP and ESRRG

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
BioGRID (two hybrid)

		EBP	ESRRG
Gene Name		emopamil binding protein (sterol isomerase)	estrogen-related receptor gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane	Nucleoplasm
	Molecular Function	C-8 Sterol Isomerase Activity Steroid Delta-isomerase Activity Transmembrane Signaling Receptor Activity Drug Transmembrane Transporter Activity Cholestenol Delta-isomerase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Steroid Hormone Receptor Activity Retinoic Acid Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding AF-2 Domain Binding
	Biological Process	Skeletal System Development Cholesterol Biosynthetic Process Drug Transmembrane Transport Signal Transduction Cholesterol Metabolic Process Hemopoiesis Small Molecule Metabolic Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Retinoic Acid Receptor Signaling Pathway
Pathways		Cholesterol biosynthesis Metabolism of lipids and lipoproteins	Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Alcohol consumption ( 23743675) Cardiac hypertrophy ( 21348951) Dialysis-related mortality ( 21546767) Major depressive disorder ( 23377640) Optic disc size (cup) ( 20395239)
Protein-Protein Interactions		4 interactors: APP EBPL ESRRG MITF	30 interactors: APP ARHGEF15 CALM1 CCDC67 DAXX DPF2 DUT EBP EIF3I ESRRA HGS KIAA1598 KIFC3 MEOX2 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PNRC1 PNRC2 PPARGC1A PPARGC1B PROX1 SP1 SRA1 SRC SRPK1 SUMO1P1 TLE1
Entrez ID		10682	2104
HPRD ID		02192	04274
Ensembl ID		ENSG00000147155	ENSG00000196482
Uniprot IDs		Q15125	B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508
PDB IDs			1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC
Enriched GO Terms of Interacting Partners?		Sterol Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Intracellular Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Steroid Metabolic Process Positive Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Alcohol Metabolic Process Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Neuron Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Melanocyte Differentiation	Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process RNA Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Transcription, DNA-templated Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Androgen Receptor Signaling Pathway Developmental Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Organ Development Regulation Of Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Development Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription System Development Negative Regulation Of RNA Biosynthetic Process Response To Lipid Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Cyclic Compound DNA-templated Transcription, Initiation Regulation Of Cellular Process Signaling Response To Hormone Steroid Metabolic Process Regulation Of Receptor Activity Cell Communication
Tagcloud ?		af ccaat delta distinguish ebps encode enhancer glucocorticoid gr gst herpes indeed indistinguishably intermediary lbd mapped potentiated potentiation pull rars reciprocally repress responsiveness simplex surprisingly thymidine truncation unable ways	aging analyzing apoa apob apoe b10 block c3 c57br chr deposits evolvement glomerular glomeruli gpatch2 haplotype inbred influencing intracapillary kctd3 mapping nzw pas perilipin reponses spanning spata17 ush2a weakly
Tagcloud (Difference) ?		af ccaat delta distinguish ebps encode enhancer glucocorticoid gr gst herpes indeed indistinguishably intermediary lbd mapped potentiated potentiation pull rars reciprocally repress responsiveness simplex surprisingly thymidine truncation unable ways	aging analyzing apoa apob apoe b10 block c3 c57br chr deposits evolvement glomerular glomeruli gpatch2 haplotype inbred influencing intracapillary kctd3 mapping nzw pas perilipin reponses spanning spata17 ush2a weakly
Tagcloud (Intersection) ?