TRIM3 and KIF21B

Number of citations of the paper that reports this interaction (PMID 24086586)
1

Data Source:
BioGRID (two hybrid)

		TRIM3	KIF21B
Gene Name		tripartite motif containing 3	kinesin family member 21B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Early Endosome	Cytoplasm Kinesin Complex Microtubule
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Nervous System Development Protein Transport Protein Ubiquitination	Microtubule-based Movement Metabolic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088) Ulcerative colitis ( 19915572)
Protein-Protein Interactions		8 interactors: ACTN4 KIF21B MYO5A TNFAIP3 UBE2D4 UBE2G2 UBE2K UBE2U	2 interactors: TK1 TRIM3
Entrez ID		10612	23046
HPRD ID		05690	12211
Ensembl ID		ENSG00000110171	ENSG00000116852
Uniprot IDs		B7Z5Y8 O75382	O75037 Q2UVF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Negative Regulation Of Toll-like Receptor 5 Signaling Pathway Negative Regulation Of CD40 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Osteoclast Proliferation Tolerance Induction To Lipopolysaccharide Cellular Protein Catabolic Process Cellular Protein Metabolic Process Protein Catabolic Process Proteolysis Protein Localization To Tight Junction Endoplasmic Reticulum Localization Regulation Of CD40 Signaling Pathway Vesicle Transport Along Actin Filament Positive Regulation Of Pinocytosis Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Vascular Wound Healing Positive Regulation Of Hepatocyte Proliferation Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Chronic Inflammatory Response Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Cellular Protein Modification Process Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway B-1 B Cell Homeostasis Intracellular Receptor Signaling Pathway Locomotion Involved In Locomotory Behavior Cellular Macromolecule Catabolic Process Protein Localization To Cell Junction Protein K6-linked Ubiquitination Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Regulation Of Hepatocyte Proliferation Protein K11-linked Deubiquitination	Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Thymidine Metabolic Process Response To Cortisol Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Parturition Response To Copper Ion Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Protein Homotetramerization Pyrimidine Nucleoside Metabolic Process Nucleoside Monophosphate Biosynthetic Process Protein Tetramerization DNA Biosynthetic Process Digestive Tract Development Digestive System Development Liver Development Response To Glucocorticoid Response To Corticosteroid Response To Toxic Substance
Tagcloud ?		amplifying bona brat depends exit fide ht2a lin41 mei named ncl1 nhl p26 perturb phenotypes preferred progenitor reconstituted repeat ring subfamily suppress suppressive transit tripartite ubch5a ubiquitinate ubiquitination	aif1 aracne attempt bioinformatics blnk ccnd2 complexity comprising connected connections csgalnact1 fam53b neighbor neighbors networks panel playing publicly reconstructed reconstruction reproducible robust sets shared signatures slc7a7 technologies tmpo whsc1
Tagcloud (Difference) ?		amplifying bona brat depends exit fide ht2a lin41 mei named ncl1 nhl p26 perturb phenotypes preferred progenitor reconstituted repeat ring subfamily suppress suppressive transit tripartite ubch5a ubiquitinate ubiquitination	aif1 aracne attempt bioinformatics blnk ccnd2 complexity comprising connected connections csgalnact1 fam53b neighbor neighbors networks panel playing publicly reconstructed reconstruction reproducible robust sets shared signatures slc7a7 technologies tmpo whsc1
Tagcloud (Intersection) ?