CDC42EP3 and SEPT6

Number of citations of the paper that reports this interaction (PMID 11584266)
38

Data Source:
BioGRID (pull down)

		CDC42EP3	SEPT6
Gene Name		CDC42 effector protein (Rho GTPase binding) 3	septin 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Actin Cytoskeleton	Condensed Chromosome Kinetochore Spindle Synaptic Vesicle Midbody Cleavage Furrow Axon Terminus
	Molecular Function	Rho GTPase Activator Activity Cytoskeletal Regulatory Protein Binding GTP-Rho Binding	Protein Binding GTP Binding
	Biological Process	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Rho GTPase Activity	Cytokinesis Viral Process
Pathways
Drugs
Diseases
GWAS		Height ( 20881960 23563607) Total ventricular volume ( 21116278)
Protein-Protein Interactions		7 interactors: CDC42 RHOQ SEPT6 SEPT7 SNCA SRPK1 UMPS	13 interactors: CDC42EP2 CDC42EP3 KDM1A MORN4 PLEKHF2 S100A4 SEPT1 SEPT2 SEPT3 SEPT5 SEPT9 TK1 WHSC1L1
Entrez ID		10602	23157
HPRD ID		09364	06716
Ensembl ID		ENSG00000163171	ENSG00000125354
Uniprot IDs		Q9UKI2	F5H1J5 Q14141 Q541S4 Q548C9
PDB IDs			2QAG
Enriched GO Terms of Interacting Partners?		Regulation Of Filopodium Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cell Morphogenesis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Regulation Of Cell Projection Assembly Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Embryonic Cell Shape Positive Regulation Of Hair Follicle Cell Proliferation Negative Regulation Of Protein Complex Assembly Regulation Of Protein Stability Organelle Organization Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Dopamine Metabolic Process Submandibular Salivary Gland Formation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Actin Filament Branching Negative Regulation Of Cellular Respiration 'de Novo' UMP Biosynthetic Process Positive Regulation Of Transport Regulation Of Cell Shape Regulation Of Microtubule-based Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Innate Immune Response Regulation Of Cellular Component Organization Establishment Of Golgi Localization Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Organelle Organization Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Intracellular Transport Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Recycling 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Epithelial-mesenchymal Cell Signaling Neuron Fate Determination Regulation Of Cellular Localization Sperm Chromatin Condensation Regulation Of Protein Heterodimerization Activity Regulation Of Dopamine Uptake Involved In Synaptic Transmission	Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Fetal Process Involved In Parturition Regulation Of Primitive Erythrocyte Differentiation Skeletal Muscle Cell Proliferation Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of L-glutamate Transport Response To Cortisol Thymidine Metabolic Process Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Synaptic Vesicle Targeting Deoxyribonucleoside Monophosphate Biosynthetic Process Histone H3-K4 Demethylation Histone H3-K27 Methylation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage
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