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CDC42EP3
Gene Name
CDC42 effector protein (Rho GTPase binding) 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Endomembrane System
Actin Cytoskeleton
Molecular Function
Rho GTPase Activator Activity
Cytoskeletal Regulatory Protein Binding
GTP-Rho Binding
Biological Process
Signal Transduction
Rho Protein Signal Transduction
Regulation Of Cell Shape
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS
Height (
20881960
23563607
)
Total ventricular volume (
21116278
)
Protein-protein Interactions
7 interactors:
CDC42
RHOQ
SEPT6
SEPT7
SNCA
SRPK1
UMPS
Entrez ID
10602
HPRD ID
09364
Ensembl ID
ENSG00000163171
Uniprot IDs
Q9UKI2
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Filopodium Assembly
Positive Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Cell Morphogenesis
Negative Regulation Of Thrombin Receptor Signaling Pathway
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Positive Regulation Of Glutathione Peroxidase Activity
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Norepinephrine Uptake
Regulation Of Cytoskeleton Organization
Regulation Of Peptidyl-serine Phosphorylation
Cytokinesis
Regulation Of Cell Projection Assembly
Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone
Regulation Of Embryonic Cell Shape
Positive Regulation Of Hair Follicle Cell Proliferation
Negative Regulation Of Protein Complex Assembly
Regulation Of Protein Stability
Organelle Organization
Regulation Of Microtubule Cytoskeleton Organization
Negative Regulation Of Dopamine Metabolic Process
Submandibular Salivary Gland Formation
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Serotonin Uptake
Actin Filament Branching
Negative Regulation Of Cellular Respiration
'de Novo' UMP Biosynthetic Process
Positive Regulation Of Transport
Regulation Of Cell Shape
Regulation Of Microtubule-based Process
Negative Regulation Of Synaptic Transmission, Dopaminergic
Negative Regulation Of Oxidative Phosphorylation
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Innate Immune Response
Regulation Of Cellular Component Organization
Establishment Of Golgi Localization
Response To Iron(II) Ion
Cellular Response To Copper Ion
Regulation Of Organelle Organization
Positive Regulation Of Metalloenzyme Activity
Positive Regulation Of Intracellular Transport
Regulation Of Neuron Apoptotic Process
Regulation Of Synaptic Vesicle Recycling
'de Novo' Pyrimidine Nucleobase Biosynthetic Process
Epithelial-mesenchymal Cell Signaling
Neuron Fate Determination
Regulation Of Cellular Localization
Sperm Chromatin Condensation
Regulation Of Protein Heterodimerization Activity
Regulation Of Dopamine Uptake Involved In Synaptic Transmission
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