RAB4B

Gene Name		RAB4B, member RAS oncogene family
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Molecular_function GTPase Activity GTP Binding GDP Binding
	Biological Process	Intracellular Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Glucose Import
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 22080838)
Protein-protein Interactions		3 interactors: EXOC5 RAB7A RABAC1
Entrez ID		53916
HPRD ID		11473
Ensembl ID		ENSG00000167578
Uniprot IDs		P61018
PDB IDs		2O52
Enriched GO Terms of Interacting Partners?		Membrane Docking Epidermal Growth Factor Catabolic Process Phagosome-lysosome Fusion Phagosome Acidification Protein To Membrane Docking Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome Phagolysosome Assembly Protein Localization To Lysosome Regulation Of Autophagic Vacuole Assembly Membrane Organization Regulation Of Vacuole Organization Intracellular PH Reduction Early Endosome To Late Endosome Transport PH Reduction Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Endosome To Lysosome Transport Bone Resorption Protein Transport Phagosome Maturation Regulation Of Intracellular PH Vesicle-mediated Transport Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Regulation Of Cellular PH Negative Regulation Of ERBB Signaling Pathway Intracellular Transport Vesicle Fusion Lysosome Organization Bone Remodeling Rab Protein Signal Transduction Positive Regulation Of Exocytosis Retrograde Transport, Endosome To Golgi Regulation Of PH Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Organelle Fusion Vacuolar Transport Protein Localization Vesicle Docking Regulation Of ERBB Signaling Pathway Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Vacuole Organization Regulation Of Autophagy
Tagcloud ?		adaptor ap1gamma budding characterised clathrin coated endocytic endosome endosomes fyve gtpases homeostasis internalised naturally perturbed rab11 reach recycled recycling sorting tf tfr tfrs traffic transferrin uncover vamp3 vesicles