CD2BP2 and ACAD11

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

		CD2BP2	ACAD11
Description		CD2 cytoplasmic tail binding protein 2	acyl-CoA dehydrogenase family member 11
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Peroxisome Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Acyl-CoA Dehydrogenase Activity Long-chain Fatty Acyl-CoA Dehydrogenase Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Very-long-chain Fatty Acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain Fatty Acyl-CoA Dehydrogenase Activity
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Processing RNA Splicing	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 32327693) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Menarche (age at onset) ( 25231870) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: ACAD11 AKNA AP2M1 CD2 CHRM3 CPSF7 CSNK2A1 LRRK1 NAT10 OGT PRPF6 PSMF1 PTBP3 SF3B4 SFPQ SMU1 SNRPB SNRPN TRAPPC6A TXNL4A WBP11 ZNHIT2	3 interacting genes: APP CD2BP2 UBC
Entrez ID		10421	84129
HPRD ID		05127	13352
Ensembl ID		ENSG00000169217	ENSG00000240303
Uniprot IDs		A0A024QZC1 O95400	Q709F0
PDB IDs		1GYF 1L2Z 1SYX 4BWS 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8RC0	2WBI
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions U5 SnRNP RNA Metabolic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly Nucleic Acid Metabolic Process Spliceosomal Complex SnRNP Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Nucleoplasm RNA Binding Negative Regulation Of Proteasomal Protein Catabolic Process U4 SnRNP Protein-containing Complex Assembly Macromolecule Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome U2-type Prespliceosome Protein-containing Complex Organization U1 SnRNP Precatalytic Spliceosome Sin3-type Complex Telomerase Holoenzyme Complex U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Negative Regulation Of Protein Catabolic Process U2-type Spliceosomal Complex Negative Regulation Of Proteolysis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity Neuroblast Delamination Spliceosomal SnRNP Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Cellular Component Assembly	Positive Regulation Of Growth Hormone Secretion Regulation Of Growth Hormone Secretion Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Translation Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Localization To Extracellular Region Hormone Secretion Insulin Secretion Peptide Hormone Secretion Hormone Transport Establishment Of Protein Localization To Extracellular Region Protein Secretion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Peptide Transport Peptide Secretion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Post-transcriptional Regulation Of Gene Expression Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Amide Transport Positive Regulation Of Hormone Secretion Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Cellular Response To Metal Ion Signal Release Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway
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