CD2BP2 and ZNHIT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD2BP2	ZNHIT2
Description		CD2 cytoplasmic tail binding protein 2	zinc finger HIT-type containing 2
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: ACAD11 AKNA AP2M1 CD2 CHRM3 CPSF7 CSNK2A1 LRRK1 NAT10 OGT PRPF6 PSMF1 PTBP3 SF3B4 SFPQ SMU1 SNRPB SNRPN TRAPPC6A TXNL4A WBP11 ZNHIT2	5 interacting genes: CD2BP2 JAKMIP1 KRTAP22-1 LONRF1 OGT
Entrez ID		10421	741
HPRD ID		05127	05200
Ensembl ID		ENSG00000169217	ENSG00000174276
Uniprot IDs		A0A024QZC1 O95400	Q9UHR6
PDB IDs		1GYF 1L2Z 1SYX 4BWS 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8RC0	1X4S
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions U5 SnRNP RNA Metabolic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly Nucleic Acid Metabolic Process Spliceosomal Complex SnRNP Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Nucleoplasm RNA Binding Negative Regulation Of Proteasomal Protein Catabolic Process U4 SnRNP Protein-containing Complex Assembly Macromolecule Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome U2-type Prespliceosome Protein-containing Complex Organization U1 SnRNP Precatalytic Spliceosome Sin3-type Complex Telomerase Holoenzyme Complex U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Negative Regulation Of Protein Catabolic Process U2-type Spliceosomal Complex Negative Regulation Of Proteolysis Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity Neuroblast Delamination Spliceosomal SnRNP Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Cellular Component Assembly
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