NMUR1 and NMU

Number of citations of the paper that reports this interaction (PMID 10894543)
33

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		NMUR1	NMU
Gene Name		neuromedin U receptor 1	neuromedin U
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Region Terminal Bouton
	Molecular Function	Neuromedin U Receptor Activity G-protein Coupled Receptor Activity Neuropeptide Receptor Activity	Receptor Binding Neuromedin U Receptor Binding
	Biological Process	Calcium Ion Transport Chloride Transport Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Neuropeptide Signaling Pathway Calcium-mediated Signaling Inositol Phosphate-mediated Signaling	Gastric Acid Secretion Regulation Of Smooth Muscle Contraction Signal Transduction G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Digestion Photoperiodism Sensory Perception Of Pain Eating Behavior Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		2 interactors: NMS NMU	5 interactors: KRTAP5-9 NMUR1 NMUR2 NOTCH2NL SNTA1
Entrez ID		10316	10874
HPRD ID		16039	05485
Ensembl ID		ENSG00000171596	ENSG00000109255
Uniprot IDs		Q9HB89	P48645
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Gastric Acid Secretion Photoperiodism Positive Regulation Of Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Eating Behavior Regulation Of Smooth Muscle Contraction Acid Secretion Sensory Perception Of Pain Feeding Behavior Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Digestion Regulation Of Muscle Contraction	Inositol Phosphate-mediated Signaling Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Calcium-mediated Signaling Neuropeptide Signaling Pathway Regulation Of Vasoconstriction By Circulating Norepinephrine Chloride Transport Second-messenger-mediated Signaling Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Regulation Of Muscle Contraction Reduction Of Food Intake In Response To Dietary Excess Activation Of Phospholipase A2 Activity Muscle Contraction Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Phospholipase A2 Activity Inorganic Anion Transport Muscle System Process Calcium Ion Transport Regulation Of Phospholipase A2 Activity Arachidonic Acid Secretion Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Response To Dietary Excess Grooming Behavior Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Synaptic Transmission Cardiac Muscle Cell Action Potential Involved In Contraction Eating Behavior Anion Transport Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Response To Pain Long-chain Fatty Acid Transport Regulation Of Cardiac Muscle Cell Contraction Activation Of Phospholipase C Activity Neuromuscular Junction Development Regulation Of Smooth Muscle Contraction Metal Ion Transport Positive Regulation Of Phospholipase C Activity Regulation Of Vasoconstriction Acid Secretion Smooth Muscle Contraction Fatty Acid Transport Cell-cell Signaling Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Hydrolase Activity
Tagcloud ?			alter animals burden carcinogen content dawley estrogen exercise exercised exercising experiment final grams hypothesized incline latency microg multiplicity overshadowed prior progressive pronounced saturated sedentary sets sprague terminated treadmill workload
Tagcloud (Difference) ?			alter animals burden carcinogen content dawley estrogen exercise exercised exercising experiment final grams hypothesized incline latency microg multiplicity overshadowed prior progressive pronounced saturated sedentary sets sprague terminated treadmill workload
Tagcloud (Intersection) ?