NMUR1 and NMU

Number of citations of the paper that reports this interaction (PubMedID 10894543)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		NMUR1	NMU
Description		neuromedin U receptor 1	neuromedin U
Image
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane	Extracellular Region Terminal Bouton
	Molecular Function	Neuromedin U Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Receptor Activity Neuromedin U Binding	Signaling Receptor Binding Protein Binding Type 1 Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Neuromedin U Receptor Binding
	Biological Process	Chloride Transport Smooth Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Calcium-mediated Signaling Positive Regulation Of Calcium-mediated Signaling	Temperature Homeostasis Gastric Acid Secretion Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Photoperiodism Positive Regulation Of Heart Rate Positive Regulation Of Heat Generation Eating Behavior Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Regulation Of Feeding Behavior Negative Regulation Of Gastric Acid Secretion Energy Homeostasis Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Positive Regulation Of Prolactin Secretion Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Feeding Behavior Regulation Of Grooming Behavior
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Corneal astigmatism ( 30306274) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432 32277301) Urinary albumin-to-creatinine ratio ( 31511532 31630189) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		2 interacting genes: NMS NMU	16 interacting genes: CYSRT1 DCDC2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP12-3 KRTAP17-1 KRTAP5-9 NBPF19 NMUR1 NMUR2 NOTCH2NLA SNTA1 TNS2
Entrez ID		10316	10874
HPRD ID		16039	05485
Ensembl ID		ENSG00000171596	ENSG00000109255
Uniprot IDs		Q9HB89	A0A0B4J202 A0A250SH36 E9PDJ7 P48645 Q86WB6
PDB IDs		7W53 7W56	7W53 7W55 7XK8
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Feeding Behavior Type 1 Neuromedin U Receptor Binding Positive Regulation Of Prolactin Secretion Regulation Of Grooming Behavior Negative Regulation Of Eating Behavior Negative Regulation Of Gastric Acid Secretion Positive Regulation Of Sensory Perception Of Pain Regulation Of Gastric Motility Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction Regulation Of Eating Behavior Gastric Acid Secretion Regulation Of Gastric Acid Secretion Negative Regulation Of Feeding Behavior Proximal Dendrite Positive Regulation Of Heat Generation Positive Regulation Of Systemic Arterial Blood Pressure Multicellular Organismal-level Homeostasis Mitotic G1 DNA Damage Checkpoint Signaling Musculoskeletal Movement Mitotic G1/S Transition Checkpoint Signaling Proline-rich Region Binding Regulation Of Sensory Perception Of Pain Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Type I Interferon-mediated Signaling Pathway Spinal Cord Motor Neuron Differentiation Regulation Of Circadian Sleep/wake Cycle Acid Secretion Regulation Of Feeding Behavior Positive Regulation Of Heart Rate Photoperiodism Positive Regulation Of Smooth Muscle Contraction Eating Behavior Positive Regulation Of Blood Pressure G Protein-coupled Receptor Signaling Pathway Temperature Homeostasis Terminal Bouton Positive Regulation Of Heart Contraction Cell Differentiation In Spinal Cord Homeostasis Of Number Of Cells Within A Tissue Insulin-like Growth Factor Receptor Signaling Pathway Rescue Of Stalled Ribosome Regulation Of Type I Interferon-mediated Signaling Pathway Ribosome Disassembly Negative Regulation Of Translational Initiation Neuromuscular Process Controlling Balance	Intermediate Filament Keratin Filament Neuromedin U Receptor Activity Neuromedin U Binding Neuropeptide Receptor Activity Epidermis Development Structural Constituent Of Skin Epidermis Positive Regulation Of Calcium-mediated Signaling
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