NMUR1 and NMS

Number of citations of the paper that reports this interaction (PMID 15635449)
17

Data Source:
HPRD (in vitro)

		NMUR1	NMS
Gene Name		neuromedin U receptor 1	neuromedin S
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Region
	Molecular Function	Neuromedin U Receptor Activity G-protein Coupled Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Calcium Ion Transport Chloride Transport Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Neuropeptide Signaling Pathway Calcium-mediated Signaling Inositol Phosphate-mediated Signaling	Neuropeptide Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		2 interactors: NMS NMU	1 interactors: NMUR1
Entrez ID		10316	129521
HPRD ID		16039	17638
Ensembl ID		ENSG00000171596	ENSG00000204640
Uniprot IDs		Q9HB89	Q5H8A3
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Gastric Acid Secretion Photoperiodism Positive Regulation Of Smooth Muscle Contraction G-protein Coupled Receptor Signaling Pathway Eating Behavior Regulation Of Smooth Muscle Contraction Acid Secretion Sensory Perception Of Pain Feeding Behavior Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Digestion Regulation Of Muscle Contraction	Inositol Phosphate-mediated Signaling Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Smooth Muscle Contraction Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Calcium-mediated Signaling Neuropeptide Signaling Pathway Chloride Transport Second-messenger-mediated Signaling Muscle Contraction Inorganic Anion Transport Muscle System Process Calcium Ion Transport
Tagcloud ?			3h acetylcholine albumin almost blocked bovine bsa chromatography column completely deae eif fold fraction fractionation guinea heat ic50 ileal inhibitory isoelectric longitudinal micrograms muscarinic partially pigs scopolamine soluble zn2
Tagcloud (Difference) ?			3h acetylcholine albumin almost blocked bovine bsa chromatography column completely deae eif fold fraction fractionation guinea heat ic50 ileal inhibitory isoelectric longitudinal micrograms muscarinic partially pigs scopolamine soluble zn2
Tagcloud (Intersection) ?