CHST4 and DCPS

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CHST4	DCPS
Gene Name		carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4	decapping enzyme, scavenger
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Integral Component Of Membrane Intrinsic Component Of Golgi Membrane	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	N-acetylglucosamine 6-O-sulfotransferase Activity Sulfotransferase Activity	RNA 7-methylguanosine Cap Binding Protein Binding M7G(5')pppN Diphosphatase Activity
	Biological Process	Carbohydrate Metabolic Process N-acetylglucosamine Metabolic Process Protein Sulfation Sulfur Compound Metabolic Process Movement Of Cell Or Subcellular Component Inflammatory Response Immune Response Cell Adhesion Cell-cell Signaling Leukocyte Tethering Or Rolling	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Gene Expression Cellular Response To Menadione Negative Regulation Of Programmed Cell Death Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay MRNA Cis Splicing, Via Spliceosome
Pathways			mRNA decay by 3' to 5' exoribonuclease Deadenylation-dependent mRNA decay
Drugs			7-Methyl-Gpppa 7n-Methyl-8-Hydroguanosine-5\'-Diphosphate N7-Methyl-Guanosine-5\'-Monophosphate Mrna Cap Analog N7-Methyl Gpppg 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine 5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CD34 DCPS	6 interactors: ANAPC10 CDC27 CHST4 CSNK2A2 GPC5 YWHAQ
Entrez ID		10164	28960
HPRD ID		07477	16787
Ensembl ID		ENSG00000140835	ENSG00000110063
Uniprot IDs		Q8NCG5	Q96C86
PDB IDs			1ST0 1ST4 1XML 1XMM 3BL7 3BL9 3BLA
Enriched GO Terms of Interacting Partners?		Extracellular Vesicular Exosome Assembly Positive Regulation Of Glial Cell Line-derived Neurotrophic Factor Secretion Negative Regulation Of Cellular Response To Heat Mesangial Cell-matrix Adhesion Cellular Response To Menadione Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Cellular Response To Hypoxia Regulation Of Macrophage Colony-stimulating Factor Production Vascular Wound Healing Paracrine Signaling Metanephric Glomerular Mesangial Cell Differentiation Regulation Of Cellular Response To Hypoxia Glomerular Endothelium Development Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Odontogenesis Metanephric Glomerulus Vasculature Development Positive Regulation Of Vasculogenesis Cell Differentiation Involved In Metanephros Development Transdifferentiation Hematopoietic Stem Cell Proliferation Negative Regulation Of Nitric Oxide Biosynthetic Process Glomerular Filtration MRNA Cis Splicing, Via Spliceosome Renal Filtration Regulation Of Vasculogenesis Metanephric Glomerulus Development Endothelial Cell Proliferation Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Angiogenesis Involved In Wound Healing Negative Regulation Of Interleukin-2 Production Negative Regulation Of Cell Death Positive Regulation Of Transforming Growth Factor Beta Production Glomerulus Vasculature Development Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Regulation Of Odontogenesis Regulation Of Cellular Response To Heat Positive Regulation Of Interleukin-10 Production Negative Regulation Of Cytokine Secretion Negative Regulation Of Tumor Necrosis Factor Production Cell Differentiation Involved In Kidney Development Metanephric Nephron Development Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Reactive Oxygen Species Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of Cell Death Negative Regulation Of Blood Coagulation Regulation Of Nitric Oxide Biosynthetic Process	Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Protein K11-linked Ubiquitination Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Regulation Of Cell Division Mitotic Spindle Assembly Checkpoint Regulation Of Organelle Organization Spindle Assembly Checkpoint Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cell Cycle Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Ubiquitination Regulation Of Proteolysis Mitotic Cell Cycle Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
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