SGK2 and HIRIP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SGK2	HIRIP3
Description		serum/glucocorticoid regulated kinase 2	HIRA interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Potassium Channel Regulator Activity Kinase Activity Transferase Activity Sodium Channel Regulator Activity Protein Serine Kinase Activity	H2A-H2B Histone Complex Chaperone Activity Protein Binding
	Biological Process	Regulation Of Cell Growth Protein Phosphorylation Response To Oxidative Stress Positive Regulation Of Transporter Activity Intracellular Signal Transduction Regulation Of Cell Population Proliferation	Chromatin Organization
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Weight ( 34074324)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 29483656)
Interacting Genes		9 interacting genes: APP DAPK1 HIRIP3 IL3RA NEDD4 NEDD4L PDPK1 PMM2 PTOV1	9 interacting genes: ABCF3 APP H2BC21 H3-4 H4C1 HIRA SGK2 SRPK1 SRPK2
Entrez ID		10110	8479
HPRD ID		06348	04531
Ensembl ID		ENSG00000101049	ENSG00000149929
Uniprot IDs		Q9HBY8	Q9BW71
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Sodium Channel Inhibitor Activity Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Regulation Of Metal Ion Transport Receptor Catabolic Process Regulation Of Monoatomic Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Positive Regulation Of Catabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Catabolic Process Neuromuscular Junction Development Regulation Of Toll-like Receptor Signaling Pathway Receptor Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Synapse Organization DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Regulation Of Dendrite Morphogenesis Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process 3-phosphoinositide-dependent Protein Kinase Activity H2A-H2B Histone Complex Chaperone Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Negative Regulation Of Cation Transmembrane Transport Receptor Internalization Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Transport Acetylcholine Receptor Activator Activity Regulation Of Protein Catabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Transport Interleukin-3 Receptor Activity Channel Inhibitor Activity Regulation Of Potassium Ion Transport Phosphomannomutase Activity GDP-D-mannose Biosynthetic Process From Fructose-6-phosphate	Chromatin Organization Chromatin Remodeling Nucleosome Assembly Protein-containing Complex Assembly Nucleosome Organization Protein-containing Complex Organization Protein-DNA Complex Assembly Chromosome Structural Constituent Of Chromatin Protein Heterodimerization Activity Cellular Component Assembly Nucleosome Response To Other Organism Positive Regulation Of Viral Genome Replication Innate Immune Response Defense Response Response To External Biotic Stimulus Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Amyloid-beta Complex Growth Cone Lamellipodium Defense Response To Symbiont Regulation Of Response To Calcium Ion Defense Response To Other Organism Amylin Binding Antibacterial Humoral Response Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Viral Process HIR Complex Positive Regulation Of Neuron Apoptotic Process Protein Phosphorylation Protein Serine Kinase Activity Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Nucleoplasm Phosphorylation Protein Serine/threonine Kinase Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Viral Life Cycle
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