EDIL3 and TBCA

Data Source: HiPPIP (Novel)

		EDIL3	TBCA
Name		EGF like and discoidin domains 3	tubulin folding cofactor A
Structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Nucleolus Cytoplasm Cytoskeleton Microtubule Microtubule Cytoskeleton
	Molecular Function	Integrin Binding Extracellular Matrix Structural Constituent Calcium Ion Binding Metal Ion Binding	RNA Binding Protein Binding Tubulin Binding Beta-tubulin Binding Protein-folding Chaperone Binding
	Biological Process	Cell Adhesion Positive Regulation Of Cell-substrate Adhesion	Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway
Pathways		Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	Post-chaperonin tubulin folding pathway
GWAS		Alzheimer's disease biomarkers ( 23419831 ) Ankylosing spondylitis ( 22138694 ) Anxiety and stress-related disorders ( 31116379 ) Asthma and hay fever ( 24388013 ) Blood trace element (Cu levels) ( 23720494 ) Chemerin levels ( 20237162 ) Loneliness ( 27629369 ) Mitochondrial DNA levels ( 25240745 ) Photic sneeze reflex ( 27182965 ) Post bronchodilator FEV1/FVC ratio ( 26634245 ) Uterine fibroid size (maximum dimension) ( 30196971 )	Appendicular lean mass ( 33097823 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Mean platelet volume ( 27863252 32888494 ) Platelet count ( 32888494 ) Platelet distribution width ( 32888494 )
Novel Interactors		3 novel interactors: MEF2C NPHP4 TBCA	7 novel interactors: AFF1 CNTN4 EDIL3 LHFPL2 PAM PHAX RAG1
Interacting Genes		4 interacting genes: ADARB1 ITGAV RBM11 RSPH1	5 interacting genes: CDC42 CEBPA ERBB3 TAF9 TERF2IP
Entrez ID		10085	6902
HPRD ID		09350	18166
Ensembl ID		ENSG00000164176	ENSG00000171530
Uniprot IDs		O43854	E5RIX8 O75347 Q6FGD7
PDB IDs		4D90	1H7C
GO Terms Enriched among Interactors		Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Double-stranded RNA Adenosine Deaminase Activity Hypoglossal Nerve Morphogenesis Adenosine To Inosine Editing Spinal Cord Ventral Commissure Morphogenesis Facial Nerve Morphogenesis Entry Into Host Cell By A Symbiont-containing Vacuole Apolipoprotein A-I-mediated Signaling Pathway Integrin Alphav-beta3 Complex Integrin Alphav-beta5 Complex Blood Vessel Development C-X3-C Chemokine Binding Alphav-beta3 Integrin-PKCalpha Complex Negative Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Lipoprotein Metabolic Process Integrin Alphav-beta1 Complex Integrin Alphav-beta6 Complex Opsonin Binding Neuregulin Binding Alphav-beta3 Integrin-IGF-1-IGF1R Complex Alphav-beta3 Integrin-HMGB1 Complex Integrin Alphav-beta8 Complex Extracellular Matrix Protein Binding Positive Regulation Of Macrophage Apoptotic Process Primary Heart Field Specification Muscle Cell Fate Determination Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Glomerulus Morphogenesis Regulation Of Synaptic Activity Nephron Tubule Epithelial Cell Differentiation Cellular Response To Trichostatin A Sinoatrial Valve Morphogenesis AMPA Selective Glutamate Receptor Signaling Pathway Radial Spoke Head 1 Radial Spoke Head 3 Radial Spoke Head Ribbon Synapse Photoreceptor Distal Connecting Cilium TRNA-specific Adenosine Deaminase Activity NMDA Selective Glutamate Receptor Signaling Pathway Ventricular Cardiac Muscle Cell Differentiation Protein Localization To Ciliary Transition Zone Adenosine Deaminase Activity Regulation Of Entry Of Bacterium Into Host Cell Transforming Growth Factor Beta Production Positive Regulation Of Behavioral Fear Response Post-chaperonin Tubulin Folding Pathway Outer Dense Fiber Deaminase Activity Positive Regulation Of Fear Response	None