TBCA and LHFPL2

		TBCA	LHFPL2
Description		tubulin folding cofactor A	LHFPL tetraspan subfamily member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytoskeleton Microtubule Microtubule Cytoskeleton	Plasma Membrane Membrane Platelet Alpha Granule Membrane
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Beta-tubulin Binding Protein-folding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway	Single Fertilization Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization
Pathways		Post-chaperonin tubulin folding pathway	Platelet degranulation
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 27863252 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494)	Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 30578418 28135244 27841878) Systolic blood pressure ( 30578418 27841878)
Interacting Genes		5 interacting genes: CDC42 CEBPA ERBB3 TAF9 TERF2IP	10 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TMEM128 TMEM147
Entrez ID		6902	10184
HPRD ID		18166	17272
Ensembl ID		ENSG00000171530	ENSG00000145685
Uniprot IDs		E5RIX8 O75347 Q6FGD7	Q6ZUX7
PDB IDs		1H7C
Enriched GO Terms of Interacting Partners?			Gap Junction Assembly Gap Junction Channel Activity Connexin Complex Gap Junction Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Renin Secretion Into Blood Stream Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Regulation Of AV Node Cell Action Potential Protein Localization To Nuclear Inner Membrane Regulation Of Atrial Cardiac Muscle Cell Action Potential Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication Negative Regulation Of Glomerular Filtration AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling Cell-cell Junction Assembly Gap Junction Hemi-channel Activity Connexin Binding Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential SA Node Cell Action Potential Atrioventricular Valve Development AV Node Cell To Bundle Of His Cell Communication Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Membrane Depolarization During Action Potential Post-chaperonin Tubulin Folding Pathway Ion Channel Regulator Activity Cell-cell Junction Organization Atrial Septum Development Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Potassium Ion Transport Cholesterol Catabolic Process Positive Regulation Of Axon Regeneration
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