ABCC5 and AK2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ABCC5	AK2
Gene Name		ATP-binding cassette, sub-family C (CFTR/MRP), member 5	adenylate kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Extracellular Vesicular Exosome Sperm Mitochondrial Sheath
	Molecular Function	ATP Binding Organic Anion Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances	Adenylate Kinase Activity ATP Binding
	Biological Process	Carbohydrate Metabolic Process Transport Pathogenesis Organic Anion Transport Glycosaminoglycan Metabolic Process Hyaluronan Metabolic Process Hyaluronan Biosynthetic Process Small Molecule Metabolic Process Transmembrane Transport	Liver Development Oxidative Phosphorylation ADP Biosynthetic Process Brain Development Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process AMP Metabolic Process DATP Metabolic Process Nucleotide Phosphorylation Nucleobase-containing Small Molecule Metabolic Process Response To Thyroid Hormone
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation ABC-family proteins mediated transport Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Glycosaminoglycan metabolism Defective SLC26A2 causes chondrodysplasias Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Hyaluronan metabolism MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates Hyaluronan biosynthesis and export MPS VI - Maroteaux-Lamy syndrome	Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: AK2 RBP5 SERPINA3 SMC2	3 interactors: ABCC5 ABCC6 SHBG
Entrez ID		10057	204
HPRD ID		06898	00047
Ensembl ID		ENSG00000114770	ENSG00000004455
Uniprot IDs		O15440	F8VZG5 G3V213 P54819
PDB IDs			2C9Y
Enriched GO Terms of Interacting Partners?		ADP Biosynthetic Process DATP Metabolic Process Meiotic Chromosome Condensation Nucleoside Diphosphate Biosynthetic Process ADP Metabolic Process AMP Metabolic Process Response To Thyroid Hormone Maintenance Of Gastrointestinal Epithelium Nucleobase-containing Small Molecule Interconversion Epithelial Structure Maintenance Deoxyribonucleoside Triphosphate Metabolic Process Mitotic Chromosome Condensation Kinetochore Organization Acute-phase Response	Primary Spermatocyte Growth Hyaluronan Biosynthetic Process
Tagcloud ?		24c 24t 388g 521c abcc2 bjc bjcancer ces1 clarifying com diarrhoea doi glucuronide hampered irinotecan journal metabolising oatp oatp1b3 personalising pfs pharmacogenetic rs2244613 rs562 slco1b1 sn ugt1a1 www	adapted ak1 aks arg attributable catalytic cold criterion dagger decreasing delta deltah denticulata efficiencies enlarges forward ka kcat kia kinetic mesophilic neocaridina odouble psychrophilic remarkable shrimp tdeltas temperatures unusual
Tagcloud (Difference) ?		24c 24t 388g 521c abcc2 bjc bjcancer ces1 clarifying com diarrhoea doi glucuronide hampered irinotecan journal metabolising oatp oatp1b3 personalising pfs pharmacogenetic rs2244613 rs562 slco1b1 sn ugt1a1 www	adapted ak1 aks arg attributable catalytic cold criterion dagger decreasing delta deltah denticulata efficiencies enlarges forward ka kcat kia kinetic mesophilic neocaridina odouble psychrophilic remarkable shrimp tdeltas temperatures unusual
Tagcloud (Intersection) ?