AK2

Description		adenylate kinase 2
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Sperm Flagellum Extracellular Exosome Sperm Mitochondrial Sheath
	Molecular Function	Nucleotide Binding AMP Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Phosphotransferase Activity, Phosphate Group As Acceptor Nucleobase-containing Compound Kinase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process ADP Biosynthetic Process Nucleotide Metabolic Process Nucleoside Monophosphate Metabolic Process Nucleobase-containing Small Molecule Interconversion AMP Metabolic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Bis(Adenosine)-5'-Pentaphosphate Imidazole
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		4 interacting genes: ABCC5 ABCC6 SHBG TRIM54
Entrez ID		204
HPRD ID		00047
Ensembl ID		ENSG00000004455
Uniprot IDs		A0A140VK93 F8VY04 F8W1A4 G3V213 P54819
PDB IDs		2C9Y
Enriched GO Terms of Interacting Partners?		ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Adenine Nucleotide Transport Purine Nucleotide Transport ATPase-coupled Transmembrane Transporter Activity Nucleotide Transport ABC-type Transporter Activity Carbohydrate Derivative Transport Carbohydrate Derivative Transmembrane Transporter Activity CGMP Transport Macromolecule Transmembrane Transporter Activity Monoatomic Anion Transmembrane Transport Organophosphate Ester Transport Monoatomic Anion Transport CAMP Transport Heme Transmembrane Transport Folate Transmembrane Transport Purine Nucleotide Transmembrane Transporter Activity Inorganic Diphosphate Transport Nucleobase-containing Compound Transport Inhibition Of Non-skeletal Tissue Mineralization Hyaluronan Biosynthetic Process Basolateral Plasma Membrane Androgen Binding Organic Acid Transport Carboxylic Acid Transport Leukotriene Transport Glutathione Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Heme Transport ABC-type Glutathione S-conjugate Transporter Activity Response To Sodium Phosphate Intracellular Phosphate Ion Homeostasis Folic Acid Transport Cyclic Nucleotide Transport Glutathione Transmembrane Transport Organic Anion Transport Efflux Transmembrane Transporter Activity Glutathione Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane ATP Hydrolysis Activity Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Oligopeptide Transmembrane Transport Xenobiotic Transmembrane Transport Response To Magnesium Ion Oligopeptide Transport Iron Ion Transmembrane Transport Glycosaminoglycan Biosynthetic Process Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity
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