ABCC5

Description		ATP binding cassette subfamily C member 5
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GO Annotations	Cellular Component	Endosome Golgi Apparatus Golgi Lumen Plasma Membrane Endosome Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Nucleotide Binding ATP Binding Organic Anion Transmembrane Transporter Activity ABC-type Xenobiotic Transporter Activity Purine Nucleotide Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity ATP Hydrolysis Activity Macromolecule Transmembrane Transporter Activity Glutathione Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity ABC-type Transporter Activity Carbohydrate Derivative Transmembrane Transporter Activity
	Biological Process	Xenobiotic Metabolic Process Xenobiotic Transmembrane Transport Purine Nucleotide Transport Hyaluronan Biosynthetic Process Glutathione Transmembrane Transport Heme Transmembrane Transport Xenobiotic Transport Transmembrane Transport CAMP Transport CGMP Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Export Across Plasma Membrane Transport Across Blood-brain Barrier Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Hyaluronan metabolism ABC-family proteins mediated transport Azathioprine ADME Paracetamol ADME
Drugs		Curcumin Curcumin sulfate
Diseases
GWAS		Anterior chamber depth ( 24603532) Basophil percentage of white cells ( 32888494) Eosinophil count ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Type 2 diabetes ( 30297969) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: AK2 RBP5 SERPINA3 SMC2 TIAM1
Entrez ID		10057
HPRD ID		06898
Ensembl ID		ENSG00000114770
Uniprot IDs		O15440
PDB IDs		8KCI 8WI2 8WI3 8WI4 8WI5
Enriched GO Terms of Interacting Partners?		Extracellular Exosome ADP Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Nucleoside Monophosphate Phosphorylation Sperm Mitochondrial Sheath Nucleobase-containing Compound Kinase Activity Phosphotransferase Activity, Phosphate Group As Acceptor AMP Kinase Activity Condensin Complex Meiotic Chromosome Condensation Positive Regulation Of Chromosome Condensation Nucleoside Diphosphate Biosynthetic Process Ribonucleoside Diphosphate Biosynthetic Process Lipid Binding Regulation Of Dopaminergic Neuron Differentiation Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Retinol Binding Retinal Binding Retinoid Binding Mitotic Chromosome Condensation Kinetochore Organization
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