GLUD2

Description		glutamate dehydrogenase 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity Glutamate Dehydrogenase (NADP+) Activity Protein Binding GTP Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, NAD Or NADP As Acceptor ADP Binding L-leucine Binding
	Biological Process	Amino Acid Metabolic Process Glutamate Metabolic Process Glutamate Biosynthetic Process L-glutamate Catabolic Process
Pathways		Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs		Glutamic acid NADH
Diseases
GWAS		Fibrinogen levels in ischemic stroke ( 26718567)
Interacting Genes		1 interacting genes: TOM1L1
Entrez ID		2747
HPRD ID		02143
Ensembl ID		ENSG00000182890
Uniprot IDs		A0A140VK14 P49448
PDB IDs		6G2U
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Clathrin Binding Protein Kinase Activator Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Golgi Stack Negative Regulation Of Mitotic Nuclear Division Regulation Of Protein Autophosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity SH3 Domain Binding Phosphatidylinositol Binding Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process Ubiquitin Binding
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