TRF-GAA1-1 and RAE1

Number of citations of the paper that reports this interaction (PubMedID 39480836)
55

Data Source:
BioGRID (unspecified method)

		TRF-GAA1-1	RAE1
Description		tRNA-Phe (anticodon GAA) 1-1	ribonucleic acid export 1
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole Fibrillar Center Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytoskeleton Mitotic Spindle Pole
	Molecular Function		RNA Binding Protein Binding Microtubule Binding Ubiquitin Binding
	Biological Process		Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery RNA Export From Nucleus MRNA Export From Nucleus Nucleocytoplasmic Transport Cell Division Regulation Of Mitotic Spindle Organization
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: RAE1	14 interacting genes: BDKRB1 BUB1 CEBPA DDX24 DHFR EIF4ENIF1 HTR2B KLRC4 KLRK1 NUMA1 NUP98 NXF1 RNU1-1 TRF-GAA1-1
Entrez ID		100189137	8480
HPRD ID			11939
Ensembl ID			ENSG00000101146
Uniprot IDs			P78406
PDB IDs			3MMY 4OWR 7F60 7F90 7VPG 7VPH
Enriched GO Terms of Interacting Partners?		Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Fibrillar Center Ubiquitin Binding RNA Export From Nucleus MRNA Export From Nucleus RNA Transport Regulation Of Microtubule Cytoskeleton Organization MRNA Transport Regulation Of Mitotic Spindle Organization Nuclear Export Mitotic Spindle Pole Spindle Pole Nuclear Pore Regulation Of Microtubule-based Process Nuclear Transport Nucleocytoplasmic Transport Microtubule Binding Nucleobase-containing Compound Transport Nuclear Envelope Chromosome Organization	MRNA Binding Positive Regulation Of Chromosome Organization Kinase Binding Nuclear Transport Nucleocytoplasmic Transport Nuclear Inclusion Body Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Peptide Binding Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Methotrexate Cortical Microtubule Anastral Spindle Assembly Cytoplasmic Microtubule Bundle Positive Regulation Of Protein Localization To Spindle Pole Body Positive Regulation Of Mitotic Spindle Elongation Nuclear Export Telomere Tethering At Nuclear Periphery Import Into Nucleus Protein Import Into Nucleus Protein Serine Kinase Activity (using GTP As Donor) Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity DNA Strand Displacement Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Prolactin Signaling Pathway Response To Dexamethasone Protein Localization To Nucleus
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