AREL1

Gene Name		apoptosis resistant E3 ubiquitin protein ligase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Ligase Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: DIABLO HTRA2 SEPT4 UBE2D1
Entrez ID		9870
HPRD ID		13794
Ensembl ID		ENSG00000119682
Uniprot IDs		O15033
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Pentacyclic Triterpenoid Metabolic Process Positive Regulation Of Endopeptidase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Peptidase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Sperm Mitochondrion Organization Cell Death Death Intrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Oxidative Stress Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Ubiquitination Positive Regulation Of Metabolic Process Protein Processing Regulation Of Apoptotic Process Cellular Response To Stress Positive Regulation Of Catalytic Activity Regulation Of Cell Death Apoptotic Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Response To Herbicide Regulation Of Endopeptidase Activity Mitochondrion Organization Protein Autoprocessing Regulation Of Mitochondrion Degradation Regulation Of Peptidase Activity Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Response To Oxidative Stress Negative Regulation Of Cell Cycle Cellular Response To Interferon-beta Sperm Capacitation Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Interferon-beta Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
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