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CD80
Gene Name
CD80 molecule
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
Coreceptor Activity
Biological Process
Epidermal Growth Factor Receptor Signaling Pathway
Cell-cell Signaling
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Viral Process
T Cell Costimulation
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
T Cell Activation
Positive Regulation Of Interleukin-2 Biosynthetic Process
Innate Immune Response
Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Alpha-beta T Cell Proliferation
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Pathways
Signaling by the B Cell Receptor (BCR)
Costimulation by the CD28 family
Signaling by FGFR in disease
PIP3 activates AKT signaling
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
PI3K events in ERBB2 signaling
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
Signalling by NGF
DAP12 interactions
GAB1 signalosome
CD28 co-stimulation
CTLA4 inhibitory signaling
CD28 dependent PI3K/Akt signaling
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by ERBB4
Signaling by Overexpressed Wild-Type EGFR in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
Constitutive PI3K/AKT Signaling in Cancer
PI3K events in ERBB4 signaling
CD28 dependent Vav1 pathway
Signaling by FGFR
Signaling by ERBB2
Signaling by EGFR
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Abatacept
Belatacept
Diseases
GWAS
Celiac disease (
20190752
)
Primary biliary cirrhosis (
23000144
21399635
)
Systemic lupus erythematosus (
23273568
)
Vitiligo (
22561518
)
Protein-protein Interactions
5 interactors:
CD274
CD28
CD86
CTLA4
NGFR
Entrez ID
941
HPRD ID
00202
Ensembl ID
ENSG00000121594
Uniprot IDs
A0N0P2
P33681
PDB IDs
1DR9
1I8L
Enriched GO Terms of Interacting Partners
?
T Cell Costimulation
Regulation Of T Cell Proliferation
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Lymphocyte Activation
Positive Regulation Of T Cell Proliferation
Regulation Of Cell Activation
Regulation Of Cell Proliferation
Positive Regulation Of Lymphocyte Proliferation
Positive Regulation Of Mononuclear Cell Proliferation
Regulation Of Cell Adhesion
Positive Regulation Of Interleukin-2 Biosynthetic Process
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cell Proliferation
Neurotrophin Signaling Pathway
Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of Immune System Process
Positive Regulation Of Interleukin-2 Production
Regulation Of Activated T Cell Proliferation
Positive Regulation Of Cytokine Production
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Negative Regulation Of Immune System Process
Cell Surface Receptor Signaling Pathway
Immune Response
Regulation Of Immune System Process
Negative Regulation Of T Cell Proliferation
Immune Response-regulating Signaling Pathway
Positive Regulation Of Cytokine Biosynthetic Process
Negative Regulation Of Lymphocyte Proliferation
Negative Regulation Of Mononuclear Cell Proliferation
Negative Regulation Of Leukocyte Proliferation
Regulation Of Cytokine Production
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Negative Regulation Of T Cell Activation
Negative Regulation Of Leukocyte Cell-cell Adhesion
Positive Regulation Of Immune Response
Negative Regulation Of Homotypic Cell-cell Adhesion
Negative Regulation Of T Cell Anergy
Positive Regulation Of Lymphotoxin A Biosynthetic Process
Regulation Of Cytokine Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of T Cell Differentiation
Negative Regulation Of Lymphocyte Activation
Negative Regulation Of Cell-cell Adhesion
Tagcloud
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amixl
atl
bc
blast
burkitt
cd54
cd58
cd86
cll
cml
costimulatory
crisis
dr
granular
hematological
hla
immuno
lgl
lymphoblastic
lymphocytic
lymphoma
malignancies
manipulating
modality
myeloblastic
neoplastic
ph1
philadelphia
sharply