PLAA

Description		phospholipase A2 activating protein
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GO Annotations	Cellular Component	Nucleus Cytoplasm Synapse Extracellular Exosome
	Molecular Function	Protein Binding Phospholipase A2 Activator Activity Ubiquitin Binding
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Inflammatory Response Signal Transduction Nervous System Development Ubiquitin Recycling Macroautophagy Positive Regulation Of Prostaglandin Biosynthetic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Response To Lipopolysaccharide Negative Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Dendrite Extension Positive Regulation Of Neuron Migration
Pathways
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Metabolite levels ( 23823483) Schizophrenia ( 20185149)
Interacting Genes		6 interacting genes: HDAC6 KPNA4 PLA2G1B UBC UBXN1 VCP
Entrez ID		9373
HPRD ID		04850
Ensembl ID		ENSG00000137055
Uniprot IDs		Q9Y263
PDB IDs		2K89 2K8A 2K8B 2K8C 3EBB
Enriched GO Terms of Interacting Partners?		Polyubiquitin Modification-dependent Protein Binding Ubiquitin Protein Ligase Binding Aggresome Assembly Regulation Of Protein Deubiquitination K48-linked Polyubiquitin Modification-dependent Protein Binding Inclusion Body Assembly VCP-NPL4-UFD1 AAA ATPase Complex Cellular Response To Misfolded Protein Response To Misfolded Protein Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Cellular Response To Topologically Incorrect Protein Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Catabolic Process Regulation Of Hippo Signaling Cellular Response To Heat Macromolecule Catabolic Process Regulation Of Proteolysis Positive Regulation Of Intracellular Signal Transduction Proteolysis Flavin Adenine Dinucleotide Catabolic Process Organelle Disassembly Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Response To Heat Response To Hydrogen Peroxide Intracellular Protein Transport Positive Regulation Of Podocyte Apoptotic Process VCP-NSFL1C Complex Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Spermidine Deacetylation Peroxidase Inhibitor Activity Ubiquitin Binding Negative Regulation Of Aggrephagy Tubulin Deacetylase Activity K6-linked Polyubiquitin Modification-dependent Protein Binding Proteasome Regulatory Particle Binding Negative Regulation Of Protein K48-linked Deubiquitination Positive Regulation Of Signal Transduction Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Arsenite Ion Mitotic Spindle Disassembly Protein-containing Complex Disassembly Positive Regulation Of Oxidative Phosphorylation
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