MTDH

Gene Name		metadherin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Tight Junction Integral Component Of Membrane Apical Plasma Membrane Nuclear Body Nuclear Membrane Intercellular Canaliculus Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Coactivator Activity Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding NF-kappaB Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Autophagy Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Tight Junction Assembly
Pathways
Drugs
Diseases
GWAS		Migraine ( 20802479)
Protein-protein Interactions		2 interactors: CSNK2A1 TOPORS
Entrez ID		92140
HPRD ID		17459
Ensembl ID		ENSG00000147649
Uniprot IDs		Q86UE4
PDB IDs
Enriched GO Terms of Interacting Partners?		Photoreceptor Cell Outer Segment Organization Retinal Cone Cell Development Retinal Rod Cell Development Camera-type Eye Photoreceptor Cell Differentiation Maintenance Of Protein Location In Nucleus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Neuron Development Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cell Death Death Protein Sumoylation Retina Layer Formation Neuron Differentiation Cell Projection Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Protein Metabolic Process Protein K48-linked Ubiquitination Eye Photoreceptor Cell Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Protein Monoubiquitination Regulation Of Apoptotic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Photoreceptor Cell Development Regulation Of Cell Proliferation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Eye Photoreceptor Cell Differentiation Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Cell Death Generation Of Neurons Neural Retina Development Retina Morphogenesis In Camera-type Eye Neurogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chaperone-mediated Protein Folding Negative Regulation Of Proteasomal Protein Catabolic Process Cell Development Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1