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LPAR2
Gene Name
lysophosphatidic acid receptor 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Endocytic Vesicle
Molecular Function
G-protein Coupled Receptor Activity
Protein Binding
Lipid Binding
PDZ Domain Binding
Lysophosphatidic Acid Receptor Activity
Biological Process
Activation Of MAPK Activity
G-protein Coupled Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Positive Regulation Of Rho Protein Signal Transduction
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS
Sphingolipid levels (
22359512
)
Protein-protein Interactions
6 interactors:
ARHGEF11
ARHGEF12
ATXN1
SLC9A3R1
SLC9A3R2
TRIP6
Entrez ID
9170
HPRD ID
05487
Ensembl ID
ENSG00000064547
Uniprot IDs
Q9HBW0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of Signaling
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Renal Phosphate Ion Absorption
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Negative Regulation Of Sodium:proton Antiporter Activity
Glutathione Transport
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Renal Sodium Ion Transport
Release Of Cytoplasmic Sequestered NF-kappaB
Neurotrophin Signaling Pathway
Cellular Phosphate Ion Homeostasis
Regulation Of Sodium:proton Antiporter Activity
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Positive Regulation Of Rho GTPase Activity
Negative Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Rho GTPase Activity
G-protein Coupled Receptor Signaling Pathway
Cell Projection Organization
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Bile Acid Secretion
Regulation Of Rho Protein Signal Transduction
Oligopeptide Transport
Apoptotic Signaling Pathway
Negative Regulation Of Sodium Ion Transport
Renal Absorption
Regulation Of Proton Transport
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Phosphate Ion Homeostasis
Signaling
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Microvillus Assembly
Axon Guidance
Negative Regulation Of Phosphorylation
Cell Communication
Regulation Of Apoptotic Process
Microvillus Organization
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Negative Regulation Of Intracellular Signal Transduction
Tagcloud
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aggressive
anchorage
cascade
colony
concurrent
cox
cxcl1
database
differentially
dramatically
dual
engraftment
ezh2
il
interleukin
multivariable
offer
predicted
proved
rationale
specimens
stanched
strategy
therapies
times
tnbc
tnbcs
triple