AKR7A2

Gene Name		aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Golgi Apparatus Cytosol Extracellular Vesicular Exosome
	Molecular Function	Alditol:NADP+ 1-oxidoreductase Activity Electron Carrier Activity Phenanthrene-9,10-epoxide Hydrolase Activity
	Biological Process	Carbohydrate Metabolic Process Cellular Aldehyde Metabolic Process Xenobiotic Metabolic Process Small Molecule Metabolic Process Daunorubicin Metabolic Process Doxorubicin Metabolic Process Oxidation-reduction Process
Pathways		Aflatoxin activation and detoxification Biological oxidations Metabolic disorders of biological oxidation enzymes Defective ACY1 causes encephalopathy
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: AKR7A3 F2 TRIM63
Entrez ID		8574
HPRD ID		04567
Ensembl ID
Uniprot IDs		O43488
PDB IDs		2BP1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Striated Muscle Atrophy Muscle Atrophy Skeletal Muscle Adaptation Negative Regulation Of Fibrinolysis Peptidyl-glutamic Acid Carboxylation Regulation Of Fibrinolysis Blood Coagulation, Intrinsic Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Platelet Activation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Metabolic Process Regulation Of Astrocyte Differentiation Fibrinolysis Regulation Of Platelet Activation Cellular Response To Dexamethasone Stimulus Positive Regulation Of Blood Coagulation Response To Dexamethasone Negative Regulation Of Glial Cell Differentiation Regulation Of Collagen Metabolic Process Positive Regulation Of Calcium Ion Transport Into Cytosol Acute-phase Response Positive Regulation Of Coagulation Response To Electrical Stimulus Positive Regulation Of Wound Healing Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Wound Healing Acute Inflammatory Response Regulation Of Glial Cell Differentiation Cellular Aldehyde Metabolic Process Regulation Of Calcium Ion Transport Into Cytosol Response To Interleukin-1 Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Calcium Ion Transport Proteolysis Regulation Of Blood Coagulation Regulation Of Gliogenesis
Tagcloud ?		aberrations aneuploid aneuploidy anxa2 belonged comparative differentially diploid endometrial endometrioid foremost genomic histopathological image imbalances ingenuity instability ipa mapped merit papillary ploidy profiling serous subgroups subjected upsc uterine validation