BRAP

Gene Name		BRCA1 associated protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Nuclear Membrane
	Molecular Function	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding Nuclear Localization Sequence Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	MAPK Cascade Ras Protein Signal Transduction Negative Regulation Of Signal Transduction Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Drinking behavior ( 21372407) Esophageal cancer ( 19698717) Hematological and biochemical traits ( 20139978) Hypothyroidism ( 22493691) LDL cholesterol ( 20686565)
Protein-protein Interactions		15 interactors: BRCA1 CDC14A CENPF CNKSR1 DDB1 HMG20A HRAS NUMA1 SYNE2 TRIM41 TRIM55 TRIM8 UBE2H USP15 USP4
Entrez ID		8315
HPRD ID		05405
Ensembl ID		ENSG00000089234
Uniprot IDs		Q59H81 Q7Z569
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Viral Release From Host Cell Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Organelle Organization Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cell Cycle Checkpoint Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Establishment Of Organelle Localization Negative Regulation Of Gene Expression Cell Cycle Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Negative Regulation Of Chromosome Organization Cellular Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation By Virus Of Viral Protein Levels In Host Cell Organelle Localization Regulation Of Mitotic Cell Cycle Protein Deubiquitination Regulation Of Cell Cycle Cell Division Cellular Protein Metabolic Process Nuclear Migration Along Microfilament G2/M Transition Of Mitotic Cell Cycle Protein Modification By Small Protein Removal Response To Radiation Negative Regulation Of Cell Cycle Nucleus Organization Chromosome Organization Positive Regulation Of Rac Protein Signal Transduction Cellular Response To Indole-3-methanol Cell Cycle Process Regulation Of Cell Cycle Process Cellular Metabolic Process Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Centriole Replication Positive Regulation Of DNA Metabolic Process Cytoskeleton Organization Regulation Of Viral Process
Tagcloud ?		centers cns complexity epistasis extraordinary fail fashion fate geographical graded gradients hyperactivation individualized ksr lis1 makes mapk midline mitogenic modulator nde1 overlapping overproliferation precision renew scaffold spatially spatiotemporally threshold