THBD

Gene Name		thrombomodulin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Signal Transduction Female Pregnancy Blood Coagulation Response To X-ray Negative Regulation Of Platelet Activation Negative Regulation Of Blood Coagulation Response To Lipopolysaccharide Leukocyte Migration Response To CAMP Negative Regulation Of Fibrinolysis
Pathways		Common Pathway Formation of Fibrin Clot (Clotting Cascade) Cell surface interactions at the vascular wall
Drugs		Drotrecogin alfa Ibuprofen
Diseases
GWAS
Protein-protein Interactions		5 interactors: F2 PF4 PROC PSENEN SERPINA5
Entrez ID		7056
HPRD ID		01764
Ensembl ID		ENSG00000178726
Uniprot IDs		P07204
PDB IDs		1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Peptidyl-glutamic Acid Carboxylation Response To Wounding Leukocyte Migration Locomotion Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Movement Of Cell Or Subcellular Component Regulation Of Blood Coagulation Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Wound Healing Cell Migration Cell Motility Negative Regulation Of Cytolysis Platelet Activation Post-translational Protein Modification Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Response To Stress Negative Regulation Of Fibrinolysis Negative Regulation Of Proteolysis Regulation Of Apoptotic Process Negative Regulation Of Protein Processing Proteolysis Positive Regulation Of Macrophage Differentiation Amyloid Precursor Protein Catabolic Process Regulation Of Cell Death Regulation Of Protein Processing Regulation Of Fibrinolysis Positive Regulation Of CAMP-mediated Signaling Inflammatory Response Blood Coagulation, Intrinsic Pathway Negative Regulation Of Astrocyte Differentiation Fusion Of Sperm To Egg Plasma Membrane Membrane Protein Intracellular Domain Proteolysis Negative Regulation Of Platelet Activation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Megakaryocyte Differentiation Plasma Membrane Fusion Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Regulation Of CAMP-mediated Signaling Notch Receptor Processing Response To Stimulus Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Tagcloud ?		acat acyltransferase alox5ap arachidonate ath atherosclerotic cbs cysthathionenine deceased gathered genomelab gexp hcats irs1 lcat ldlr lecithin lipoxygenase lpl malaysian metallopeptidase methylenetetrahydrofolate mmp9 mortem mthfr ncat predetermined tgfbr2 thrombomodulin