TFR2

Gene Name		transferrin receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane
	Molecular Function	Transferrin Receptor Activity
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		Hematocrit ( 19862010) Hematological parameters ( 19820697) Iron levels ( 21208937) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517)
Protein-protein Interactions		3 interactors: HFE SOCS3 TF
Entrez ID		7036
HPRD ID		05282
Ensembl ID		ENSG00000106327
Uniprot IDs		Q9UP52
PDB IDs
Enriched GO Terms of Interacting Partners?		Iron Ion Transport Cellular Iron Ion Homeostasis Iron Ion Homeostasis Transition Metal Ion Homeostasis Cellular Response To Iron Ion Starvation Multicellular Organismal Homeostasis Spongiotrophoblast Differentiation Iron Ion Import Into Cell Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Branching Involved In Labyrinthine Layer Morphogenesis Cellular Chemical Homeostasis Ion Homeostasis Iron Ion Import Spongiotrophoblast Layer Development Multicellular Organismal Iron Ion Homeostasis Cellular Homeostasis Trophoblast Giant Cell Differentiation Regulation Of Interferon-gamma-mediated Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of JAK-STAT Cascade Labyrinthine Layer Morphogenesis Growth Hormone Receptor Signaling Pathway Response To Stress Cellular Response To Growth Hormone Stimulus Embryonic Placenta Morphogenesis Metal Ion Transport Chemical Homeostasis Regulation Of Immune Response Transferrin Transport Cell Differentiation Involved In Embryonic Placenta Development Placenta Blood Vessel Development Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Regulation Of Type I Interferon-mediated Signaling Pathway Hormone Biosynthetic Process JAK-STAT Cascade Cation Transport Labyrinthine Layer Development Retina Homeostasis Regulation Of Insulin Receptor Signaling Pathway Immune Response Regulation Of Immune System Process Platelet Degranulation Reproductive Process Homeostatic Process Regulation Of Cellular Response To Insulin Stimulus
Tagcloud ?		arrays chemotaxis complement congenital count counts cxcr2 exome frameshift genotyped hbb hematocrit hematological hematopoiesis hemoglobin identifying missense neutropenia pedigree platelet resequencing separate sh2b3 splice traits tubb1 val617phe variants wbc